Equipment source: ARIS

Nanomanipulator of individual molecules based on TIRF and optical tweezer

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Purpose of equipment
The LUMICKS C-Trap EDGE 350 allows simultaneous TIRF measurements in three channels (488nm, 532nm and 638nm), imaging of fibres or other structures on the glass surface without labels (IRM - Interference Reflection Microscopy), and the use of optical tweezers for sample manipulation and force measurements. The instrument is coupled to a 6 channel microfluidic system. The single-molecule nanomanipulator thus combines three optical methods to detect molecules and particle movements with an accuracy of up to 1 nanometre.
Access of equipment
Responsible for equipment: PhD Martina Mohorčič
Upon agreement with the administrator dr. Ajasja Ljubetič (ajasja,ljubetic@ki.si)
ARIS research and infrastructure programmes (2) Legend
no. Code Title Period Head No. of publications
1.  I0-0003  Infrastructural program of National institute of Chemistry  1/1/2022 - 12/31/2027  PhD Janez Plavec  2,041 
2.  P4-0176  Synthetic biology and immunology  1/1/2022 - 12/31/2027  PhD Roman Jerala  2,667 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  0104  National Institute of Chemistry  Ljubljana  5051592000  23,477 
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