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Projects / Programmes source: ARIS

Assessment of A-V Conduction by Noninvasive Measurements of the PR Interval Signal

Research activity

Code Science Field Subfield
3.06.00  Medical sciences  Cardiovascular system   

Code Science Field
B470  Biomedical sciences  Physiology 
B530  Biomedical sciences  Cardiovascular system 
Keywords
High resolution ECG, sympathetic tone, vagal tone, heart rate variability, conduction of cardiac impulse, anaesthesia, respiratory sinus arrhythmia, antiarrhythmic drugs
Evaluation (rules)
source: COBISS
Researchers (4)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  08797  MSc Tatjana Drglin  Cardiovascular system  Researcher  1998 - 1999  33 
2.  05922  PhD Živa Melik  Cardiovascular system  Researcher  1998 - 1999  107 
3.  08223  Daniel Peterec  Cardiovascular system  Researcher  1998 - 1999  30 
4.  04341  PhD Vito Starc  Cardiovascular system  Head  1998 - 1999  270 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  48,216 
Abstract
A noninvasive method was developed to measure beat to beat fluctuations of the P-Q interval, smaller than 1 msec. For this purpose a software program was developed to analyze data obtained from high resolution ECG measurements in humans. The method will be used to study (a) P-Q interval changes in normal young people as a response to change in the position of the body after tilting the body, (b) P-Q interval changes during anaesthesia and after recovery from it, (c) in coronary patients, and (d) in the rabbit before and after digitalization. The method will be modified for measurements of Q-T interval fluctuations and used to study the response of the Q-T interval after changing the position by tilting the body, and after breath holding, as well as to measure changes in the Q-T interval fluctuations in coronary patients as compared to the normal control group. For the purpose of interpretation of the measurements, a mathematical model will be built, based on electrophysiogical properties of AV node.
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