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International projects source: SICRIS

Multi-target paradigm for innovative ligand identification in the drug discovery process (MuTaLig)

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Researchers (3)
no. Code Name and surname Research area Role Period No. of publications
1.  01463  PhD Danijel Kikelj  Pharmacy  Researcher  2016 - 2020  566 
2.  15293  PhD Črtomir Podlipnik  Chemistry  Researcher  2016 - 2020  217 
3.  28334  PhD Tihomir Tomašić  Pharmacy  Researcher  2016 - 2020  374 
Organisations (2)
no. Code Research organisation City Registration number No. of publications
1.  0103  University of Ljubljana, Faculty of Chemistry and Chemical Technology  Ljubljana  1626990  23,083 
2.  0787  University of Ljubljana, Faculty of Pharmacy  Ljubljana  1626973  17,159 
Abstract
The aim of this COST Action is to join highly-qualified research teams working in disciplines around the field of medicinal chemistry, into a novel network devoted to the multi-target issue in drug discovery. The choice of this theme is related to its marked multidisciplinary character, which can ensure a strong interaction among all COST Action participants. Currently, an important and emerging issue in modern drug discovery is to design novel or identify existing bioactive compounds, endowed with the capability to interact selectively with two or more macromolecular targets, exerting their effects against certain therapeutic goals in a synergic fashion. This leading concept stimulated this COST Action focusing on novel ligands able to recognize selected multiple targets, to promote closer scientific links among European research groups involved in medicinal chemistry field at both academic and industrial level. The research competencies of the network will span around medicinal chemistry, from synthetic chemistry, natural products and biophysics to theoretical chemistry, molecular modelling and biological screening.
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