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Projects / Programmes
Elektrokemoterapija - nov pristop k zdravljenju raka (Slovene)
Research activity
| Code | Science | Field | Subfield |
|---|---|---|---|
| 3.04.00 | Medical sciences | Oncology |
| Code | Science | Field |
|---|---|---|
| B007 | Biomedical sciences | Medicine (human and vertebrates) |
| B520 | Biomedical sciences | General pathology, pathological anatomy |
Keywords
electrochemotherapy, bleomycin, cisplatin, cells cultured, neoplasms experimental, neoplasms
Evaluation
(metodology)
Citations
Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
Organisations (1) , Researchers (13)
0302 Institute of Oncology Ljubljana
| no. | Code | Name and surname | Research area | Role | Period | No. of publicationsNo. of publications |
|---|---|---|---|---|---|---|
| 1. | 00705 | Oncology | Researcher | 1996 - 2001 | 203 | |
| 2. | 02636 | Oncology | Researcher | 1996 - 2001 | 19 | |
| 3. | 14575 | Oncology | Researcher | 1996 - 2001 | 1,582 | |
| 4. | 03286 | Oncology | Researcher | 1996 - 2001 | 1 | |
| 5. | 12179 | Oncology | Researcher | 1996 - 2001 | 782 | |
| 6. | 03282 | Oncology | Researcher | 2000 - 2001 | 16 | |
| 7. | 03171 | Medical sciences | Researcher | 1998 - 2001 | 286 | |
| 8. | 04402 | Oncology | Researcher | 1996 - 2001 | 43 | |
| 9. | 04377 | Oncology | Researcher | 1996 - 2001 | 31 | |
| 10. | 12229 | Mathematics | Researcher | 1996 - 2001 | 9 | |
| 11. | 08750 | Oncology | Researcher | 1996 - 2001 | 258 | |
| 12. | 08800 | Oncology | Head | 1996 - 2001 | 1,617 | |
| 13. | 11949 | Oncology | Researcher | 1999 - 2001 | 711 |
Abstract
Electroporation of cells by short intense electric pulses induces transient permeabilization of plasma membrane, enabling access of the nonpermeableor poorly permeable drugs into cytosol. The method by which electroporation increases the access of chemotherapeutic drugs into the cells is called electrochemotherapy. The aim of this study is to optimize electrochemotherapy with chemotherapeutics bleomycin and cisplatin. The study is designed on in vitro level, tumor models in mice and as a clinical study in cancer patients.