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Projects / Programmes source: ARIS

Elektrokemoterapija - nov pristop k zdravljenju raka (Slovene)

Research activity

Code Science Field Subfield
3.04.00  Medical sciences  Oncology   

Code Science Field
B007  Biomedical sciences  Medicine (human and vertebrates) 
B520  Biomedical sciences  General pathology, pathological anatomy 
Keywords
electrochemotherapy, bleomycin, cisplatin, cells cultured, neoplasms experimental, neoplasms
Evaluation (rules)
source: COBISS
Researchers (13)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  00705  PhD Marija Auersperg  Oncology  Researcher  1996 - 2001  203 
2.  02636  PhD Marija Bizjak-Schwarzbartl  Oncology  Researcher  1996 - 2001  19 
3.  14575  PhD Maja Čemažar  Oncology  Researcher  1996 - 2001  1,427 
4.  03286  Vera Čoroli  Oncology  Researcher  1996 - 2001 
5.  12179  PhD Tanja Čufer  Oncology  Researcher  1996 - 2001  774 
6.  03282  Franc Guna  Oncology  Researcher  2000 - 2001  16 
7.  03171  PhD Aleksandra Markovič-Predan  Medical sciences  Researcher  1998 - 2001  284 
8.  04402  Franci-Stanko Marolt  Oncology  Researcher  1996 - 2001  43 
9.  04377  Tadeja Movrin-Stanovnik  Oncology  Researcher  1996 - 2001  31 
10.  12229  Gorazd Noč  Mathematics  Researcher  1996 - 2001 
11.  08750  PhD Zvonimir Rudolf  Oncology  Researcher  1996 - 2001  258 
12.  08800  PhD Gregor Serša  Oncology  Head  1996 - 2001  1,511 
13.  11949  PhD Borut Štabuc  Oncology  Researcher  1999 - 2001  677 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0302  Institute of Oncology Ljubljana  Ljubljana  5055733000  15,468 
Abstract
Electroporation of cells by short intense electric pulses induces transient permeabilization of plasma membrane, enabling access of the nonpermeableor poorly permeable drugs into cytosol. The method by which electroporation increases the access of chemotherapeutic drugs into the cells is called electrochemotherapy. The aim of this study is to optimize electrochemotherapy with chemotherapeutics bleomycin and cisplatin. The study is designed on in vitro level, tumor models in mice and as a clinical study in cancer patients.
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