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Projects / Programmes source: ARIS

Različni imunski markerji in njihov vpliv na zgodnejše odkrivanje in zdravljenje sistemskih avtoimunskih bolezni in sorodnih stanj (Slovene)

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Research activity

Code Science Field Subfield
3.01.00  Medical sciences  Microbiology and immunology   

Code Science Field
B007  Biomedical sciences  Medicine (human and vertebrates) 
B500  Biomedical sciences  Immunology, serology, transplantation 
Keywords
Systemic autoimmune diseases, antiphospholipid antibodies, antiendothelial antibodies, antibodies against ß2-glycoprotein I
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (11)
no. Code Name and surname Research area Role Period No. of publications
1.  19209  PhD Aleš Ambrožič  Microbiology and immunology  Researcher  1996 - 2001  220 
2.  00781  PhD Borut Božič  Microbiology and immunology  Researcher  2000 - 2001  601 
3.  16362  PhD Saša Čučnik  Microbiology and immunology  Researcher  1996 - 2001  386 
4.  12154  PhD Maja Hojnik  Microbiology and immunology  Researcher  1998 - 2001  45 
5.  02066  PhD Tatjana Kveder  Microbiology and immunology  Researcher  1998 - 2001  275 
6.  02087  MSc Boris Lestan  Microbiology and immunology  Researcher  1996 - 2001  69 
7.  10080  PhD Dušan Logar  Microbiology and immunology  Researcher  1998 - 2001  128 
8.  13602  PhD Sonja Praprotnik  Microbiology and immunology  Researcher  1998 - 2001  372 
9.  07180  PhD Blaž Rozman  Microbiology and immunology  Head  1998 - 2001  563 
10.  10645  MSc Alenka Šipek Dolničar  Microbiology and immunology  Researcher  1998 - 2001  37 
11.  13601  PhD Matija Tomšič  Microbiology and immunology  Researcher  1999 - 2001  764 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,498 
Abstract
Positive tests for autoantibodies against self-antigens may correlate with specific clinical conditions, disease features that are or can be of autoimmune origin. Early detection and appropriate interpretation of the presence of these antibodies may encourage earlier treatment and also offers a means of monitoring disease progress and response to the therapy. Project was designed to 1/ add some insight into the mechanisms leading to the production of autoantibodies, their specific role in certain rheumatic and other non-organ specific autoimmune conditions or diseases with suspected autoimmune aetiology including the examination of test systems on an international level for the detection of autoantibodies with the sensitivity and reproducibility of different methodologies and 2/ define the significance of molecular structures of some target antigens (with special emphasis on the phospholipids and endothelial cell antigens) in the production of autoantibodies in animal models and human diseases together with the introduction of relevant new research technique (immune blotting, monoclonal antibodies, recombinant antigens, including deletion mutants, cell cultures).
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