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Projects / Programmes source: ARIS

Nivo cistatina C in katepsinov B, H in L v bioloških tekočinah zdravih oseb in astmatikov (Slovene)

Research activity

Code Science Field Subfield
3.01.00  Medical sciences  Microbiology and immunology   

Code Science Field
B540  Biomedical sciences  Respiratory system 
B190  Biomedical sciences  Clinical chemistry 
Keywords
circadian variations, asthma, cystatin C, cathepsin B, cathepsin H, cathepsin L
Evaluation (rules)
source: COBISS
Researchers (5)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  10291  PhD Nina Cimerman  Pharmacy  Researcher  1999 - 2001  117 
2.  04648  PhD Janko Kos  Biotechnical sciences  Researcher  2000 - 2001  1,158 
3.  06394  Marta Krašovec  Pharmacy  Researcher  2000 - 2001  83 
4.  06630  PhD Pika Meško Brguljan  Biochemistry and molecular biology  Head  2000 - 2001  345 
5.  09808  PhD Jurij Šorli  Cardiovascular system  Researcher  1998 - 2001  354 
Organisations (2)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0259  Krka, tovarna zdravil, d.d., Novo mesto (Slovene)  Novo mesto  5043611  3,793 
2.  1613  University Clinic of Respiratory and Allergic Diseases  Golnik  1190997  7,104 
Abstract
The objective of this project is to determine levels of cystatin C and cathepsins B, H and L in biological fluids of healthy and asthmatic subjects. The purpose is also to establish their normal serum base-line circadian characteristics and their deviations before and after cortisteroid and cyclosporine A treatment. The results may provide better understanding of the role of cysteine proteinases and their inhibitors in pathophysiological mechanisms and may be of clinical interest as additional biochemical parameters for monitoring the disease and its therapy.
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