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Projects / Programmes source: ARIS

Prognostic value of uPA, PAI 1 and PAI 2 in solid tumors

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Research activity

Code Science Field Subfield
3.04.00  Medical sciences  Oncology   

Code Science Field
B007  Biomedical sciences  Medicine (human and vertebrates) 
B200  Biomedical sciences  Cytology, oncology, cancerology 
Keywords
plasminogen activator, plasminogen activator inhibitors, prognosis, breast cancer, bladder cancer
Evaluation (rules)
source: COBISS
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (17)
no. Code Name and surname Research area Role Period No. of publications
1.  05071  PhD Ankica Babič  Engineering sciences and technologies  Researcher  1998 - 1999  104 
2.  08616  PhD Matej Bračko  Medical sciences  Researcher  1997 - 1999  197 
3.  15832  Olga Cerar  Medical sciences  Researcher  1997 - 1999  100 
4.  03289  Jožica Červek  Medical sciences  Researcher  1997 - 1999  204 
5.  12179  PhD Tanja Čufer  Medical sciences  Head  1997 - 1999  773 
6.  15834  PhD Tanja Južnič Šetina  Medical sciences  Researcher  1997 - 1999  57 
7.  12224  PhD Borut Kragelj  Medical sciences  Researcher  1997 - 1999  78 
8.  05278  PhD Jurij Lindtner  Medical sciences  Researcher  1997 - 1999  163 
9.  07187  PhD Andrej Mašera  Medical sciences  Researcher  1998 - 1999  129 
10.  07228  PhD Zdenka Ovčak  Medical sciences  Researcher  1998 - 1999  78 
11.  15835  MSc Bojana Pajk  Medical sciences  Researcher  1997 - 1999  86 
12.  08754  Gabrijela Petrič-Grabnar  Medical sciences  Researcher  1997 - 1999  66 
13.  08750  PhD Zvonimir Rudolf  Medical sciences  Researcher  1997 - 1999  257 
14.  08800  PhD Gregor Serša  Medical sciences  Researcher  1997 - 1999  1,475 
15.  00712  PhD Janez Škrk  Medical sciences  Researcher  1998 - 1999  173 
16.  07195  PhD Ivan Vrhovec  Medical sciences  Researcher  1997 - 1999  116 
17.  11747  PhD Branko Zakotnik  Medical sciences  Researcher  1997 - 1999  420 
Organisations (3)
no. Code Research organisation City Registration number No. of publications
1.  0302  Institute of Oncology Ljubljana  Ljubljana  5055733000  14,834 
2.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  45,607 
3.  1538  University of Ljubljana, Faculty of Electrical Engineering  Ljubljana  1626965  27,347 
Abstract
The prognosis of cancer patients depends largely on the ability of cancer cells to invade the surrounding tissue and to metastasize. These processes are influenced by tumor-associated proteases among which serine proteases and their inhibitors may play a central role. The aim of our study is to determine the content of serine protease uPA and its inhibitors PAI 1 and PAI 2, in primary tumors of the breast and urinary bladder, and to establish their prognostic value. It is hoped that the results of our study could be used for a more rational treatment planning in patients with primary cancers of the breast and urinary bladder, thus improving their survival.
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