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Projects / Programmes source: ARIS

Analysis of late sequelae of cancer treatment in childhood

Research activity

Code Science Field Subfield
3.04.00  Medical sciences  Oncology   

Code Science Field
B660  Biomedical sciences  Pediatrics 
B200  Biomedical sciences  Cytology, oncology, cancerology 
Keywords
malignant neoplasms, children, late effect
Evaluation (rules)
source: COBISS
Researchers (3)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  05318  PhD Berta Jereb  Oncology  Head  1999  350 
2.  12224  PhD Borut Kragelj  Oncology  Researcher  1998 - 1999  81 
3.  08754  Gabrijela Petrič-Grabnar  Oncology  Researcher  1999  66 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0302  Institute of Oncology Ljubljana  Ljubljana  5055733000  15,493 
Abstract
The results of treatment of malignant diseases in children have dramatically improved during the last decades, from about 10% to about 75% overall survival. Studies of late sequelae of treatment for childhood cancer are at present the major concern of pediatric oncology. The aim of the study is to identify groups of patients at risk for late sequelae, to define their causes (genetic damage) and analyze other variables, such as radiation and cytotoxic drugs, known for their toxic effects. The aims of the project are to find the somatic and psychological late sequelae of cancer treatment in childhood; to analyze their correlation with such clinical factors as patient''s age, mode of treatment, diagnosis, etc. The following is possible on the basis of the findings: a) prevent these sequelae with treatment modifications of the children treated at present; b) treat late sequelae; c) incorporate the results of the study into the Medical School curriculum.
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