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Projects / Programmes source: ARIS

Charactheristics of development, maturation and fertilization capacity of oocytes in ivf and icsi procedures in natural cycle

Research activity

Code Science Field Subfield
3.05.00  Medical sciences  Human reproduction   

Code Science Field
B570  Biomedical sciences  Obstetrics, gynaecology, andrology, reproduction, sexuality 
Keywords
IVF, ICSI, natural cycle, fertilization, maturation in vitro, fertilization failure, follicle-ultrasound, follicle-Doppler, estradiol monitoring
Evaluation (rules)
source: COBISS
Researchers (6)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  03456  PhD Radovan Breznik  Human reproduction  Researcher  1998 - 1999  138 
2.  08397  PhD Vida Gavrić Lovrec  Human reproduction  Researcher  1998 - 1999  231 
3.  11040  PhD Borut Kovačič  Human reproduction  Researcher  1998 - 1999  374 
4.  15713  MSc Vida Petrovič  Human reproduction  Researcher  1998 - 1999  19 
5.  15711  PhD Milan Reljič  Human reproduction  Researcher  1998 - 1999  297 
6.  08996  PhD Veljko Vlaisavljević  Human reproduction  Head  1998 - 1999  594 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0334  University Medical Centre Maribor  Maribor  5054150000  22,762 
Abstract
The aim of the project is to establish factors that influence follicle development in 300 natural cycles for IVF and ICSI procedure. Echographic end endocrinologyc parameters that can influence follicular development will be analyzed. Computer graphic for recognition of follicle appereance will be developed. The results of serial measurements of blood flow by Doppler ultrasound throuthout periovulatory period will be compared with endocrinologic findings and oocyte fertilization. Granuloza cell proliferation will be studied under in vitro condition and compared with oocyte fertilization and embryo development. DNA and miotic spindle in nonfertilized oocytes after ICSI procedure will be studied using imunofluorescence technology. Ability of immature oocytes to mature in vitro and their potential for fertilization and embryo development will be analyzed.
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