Projects / Programmes
Charactheristics of development, maturation and fertilization capacity of oocytes in ivf and icsi procedures in natural cycle
Code |
Science |
Field |
Subfield |
3.05.00 |
Medical sciences |
Human reproduction |
|
Code |
Science |
Field |
B570 |
Biomedical sciences |
Obstetrics, gynaecology, andrology, reproduction, sexuality |
IVF, ICSI, natural cycle, fertilization, maturation in vitro, fertilization failure, follicle-ultrasound, follicle-Doppler, estradiol monitoring
Researchers (6)
Organisations (1)
Abstract
The aim of the project is to establish factors that influence follicle development in 300 natural cycles for IVF and ICSI procedure. Echographic end endocrinologyc parameters that can influence follicular development will be analyzed. Computer graphic for recognition of follicle appereance will be developed. The results of serial measurements of blood flow by Doppler ultrasound throuthout periovulatory period will be compared with endocrinologic findings and oocyte fertilization. Granuloza cell proliferation will be studied under in vitro condition and compared with oocyte fertilization and embryo development. DNA and miotic spindle in nonfertilized oocytes after ICSI procedure will be studied using imunofluorescence technology. Ability of immature oocytes to mature in vitro and their potential for fertilization and embryo development will be analyzed.