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Projects / Programmes source: ARIS

Cancerogenesis of thyroid cells in vitro and in vivo conditions

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Research activity

Code Science Field Subfield
3.04.00  Medical sciences  Oncology   

Code Science Field
B200  Biomedical sciences  Cytology, oncology, cancerology 
B210  Biomedical sciences  Histology, cytochemistry, histochemistry, tissue culture 
Keywords
thyroid, cell culture, rat, radiation, cancerogenesis, tumour, transplantation, morphometry, immunocytochemistry, chromosomes, in situ hybridization
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (8)
no. Code Name and surname Research area Role Period No. of publications
1.  11308  PhD Andrej Cör  Oncology  Researcher  1997 - 1999  409 
2.  18263  Miha Elsner    Researcher  1997 - 1999  0 
3.  18266  Nada Godnič    Researcher  1998 - 1999  0 
4.  18267  Andreja Lesar    Researcher  1997 - 1999  0 
5.  08593  PhD Zdenka Pajer-Likozar  Oncology  Head  1997 - 1999  47 
6.  03679  Magda Pezdirc    Researcher  1997 - 1999  11 
7.  07798  PhD Draga Štiblar Martinčič  Oncology  Researcher  1999  161 
8.  18268  Danica Šurev    Researcher  1997 - 1999  0 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  48,203 
Abstract
The most concerning concequences of radiation are malignant diseases and genetic alterations that reflect to the descendant. The connections between the thyroid tumours and different kind of radiations, also in the therapeutic purposes, are well known. The aim of proposed project is to make such a model of thyroid cancerogenesis that will make possible the comparison of the results between in vitro and in vivo investigations. On this model we would like to study the radiation cancerogenesis of the thyroid cells with the contemporary methods and to establish the genom alterations that lead to the tumour transformation. We also want to verify the hypothesis that inactive thyroid cells are less sensitive to radiation that active ones.
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