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Projects / Programmes source: ARIS

Role of proteases and their inhibitors in apoptosis

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Research activity

Code Science Field Subfield
1.05.00  Natural sciences and mathematics  Biochemistry and molecular biology   

Code Science Field
P004  Natural sciences and mathematics  Biochemistry, Metabolism 
Keywords
apoptosis, proteases, inhibitors, caspases, cathepsins, proteolysis, cystatins
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (3)
no. Code Name and surname Research area Role Period No. of publications
1.  10502  PhD Nataša Kopitar Jerala  Biochemistry and molecular biology  Researcher  1999 - 2001  239 
2.  14829  PhD Veronika Stoka  Biochemistry and molecular biology  Researcher  1999 - 2001  237 
3.  07561  PhD Boris Turk  Biochemistry and molecular biology  Head  1999 - 2001  1,037 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  90,664 
Abstract
The proposed project deals with biochemical studies of apoptosis and the proteases involved, emphasis being on caspases. New mammalian protein inhibitors of caspases will be sought and their mechanism of interaction with caspases investigated. The activation mechanism of caspases, as well as the role of caspase 7 in apopotsis, will also be subjects of our investigation. The proposed research programme will contribute to a better understanding of proteolysis and apoptosis and its regulation in normal and pathological conditions.
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