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Projects / Programmes source: ARIS

Measurements of hormone secretion from single cells utilizing a digital signal processor

Research activity

Code Science Field Subfield
3.03.00  Medical sciences  Neurobiology   

Code Science Field
B140  Biomedical sciences  Clinical physics, radiology, tomography, medical instrumentation 
Keywords
exocytosis, cell membrane, membrane capacitance, electrophysiology
Evaluation (rules)
source: COBISS
Researchers (5)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  06846  Sonja Grilc  Neurobiology  Researcher  1999 - 2001  57 
2.  01187  PhD Marjan Kordaš  Neurobiology  Researcher  1999 - 2001  294 
3.  18825  PhD Irina Milisav Ribarič  Neurobiology  Researcher  1999 - 2001  154 
4.  12266  PhD Marjan Slak Rupnik  Metabolic and hormonal disorders  Researcher  1998 - 2001  350 
5.  03702  PhD Robert Zorec  Neurobiology  Head  1998 - 2001  802 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  48,429 
Abstract
Exocytosis mediates hormone secretion from cells. Although this is a ubiquitous process of all eukaryonic cells, little is known about the mechanisms controlling it. One reason for this is that electrophysiological methods to detect hormone secretion at cellular level are technically demanding, thus used in only in a small number of specialiezed laboratories. The aim of this project is to develop a method of analysis of cell membrane admittance utilizing a digital signal processor, which will make measurements simpler, will increase the aplicability in experiments and will be more interesting for commercial production (shorter time for production and calibration of instruments).
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