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Projects / Programmes source: ARRS

Biofarmacevtske lastnosti, sinteza in aktivnost spojin kinolonov s kovinskimi atomi (Slovene)

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Research activity

Code Science Field Subfield
1.09.00  Natural sciences and mathematics  Pharmacy   

Code Science Field
T410  Technological sciences  Pharmaceuticals and related technologies 
Keywords
fluoroquinolones, pharmacokinetic properties, metallic complexes, antimicrobial activity, erythrocyte uptake of drugs
Evaluation (rules)
source: COBISS
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (15)
no. Code Name and surname Research area Role Period No. of publications
1.  11124  PhD Marija Bogataj  Natural sciences and mathematics  Researcher  1999 - 2001  369 
2.  03439  PhD Peter Bukovec  Natural sciences and mathematics  Researcher  1999 - 2001  543 
3.  17432  Margareta Cof    Researcher  1999 - 2001  0 
4.  11789  PhD Mirjana Gašperlin  Natural sciences and mathematics  Researcher  2000 - 2001  584 
5.  16107  PhD Iztok Grabnar  Natural sciences and mathematics  Researcher  1999 - 2001  425 
6.  17433  Tatjana Hrovatič    Researcher  1999 - 2001  0 
7.  17434  Mihaela Kolarev    Researcher  1999 - 2001  0 
8.  00184  PhD Franc Kozjek  Natural sciences and mathematics  Researcher  1999 - 2001  486 
9.  11122  PhD Albin Kristl  Natural sciences and mathematics  Principal Researcher  1999 - 2001  347 
10.  09032  PhD Julijana Kristl  Natural sciences and mathematics  Researcher  2000 - 2001  925 
11.  17430  Nevenka Lilik    Researcher  1999 - 2001  0 
12.  06086  PhD Aleš Mrhar  Natural sciences and mathematics  Researcher  1999 - 2001  1,161 
13.  09066  PhD Stanislav Primožič  Natural sciences and mathematics  Researcher  1999 - 2001  302 
14.  09031  PhD Stanko Srčič  Natural sciences and mathematics  Researcher  1999 - 2001  673 
15.  16025  PhD Elizabeta Tratar Pirc  Natural sciences and mathematics  Researcher  1999 - 2001  125 
Organisations (2)
no. Code Research organisation City Registration number No. of publications
1.  0103  University of Ljubljana, Faculty of Chemistry and Chemical Technology  Ljubljana  1626990  22,061 
2.  0787  University of Ljubljana, Faculty of Pharmacy  Ljubljana  1626973  16,357 
Abstract
The aim of the project is the synthesis together with structural, biopharmaceutic and microbiological assessment of the properties od metal-quinolone compounds. Transport properties and therapeutic potential of compounds of the fluoroquinolone type that are bound in a complex with metal atoms potentially exerting synergistic effects will be studied. Special interest will be put on the influence of the presence and the type of metallic atom in in vitro and ex-vivo systems on the rate and extent of the transport of the quinolones accross biologic membranes.
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