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Projects / Programmes source: ARIS

Smart materials for bioapplications

Research activity

Code Science Field Subfield
2.02.02  Engineering sciences and technologies  Chemical engineering  Separation processes 

Code Science Field
T350  Technological sciences  Chemical technology and engineering 

Code Science Field
2.04  Engineering and Technology  Chemical engineering  
Keywords
Chemical engineering, subcritical and supercritical fluids, smart materials, bioaplications.
Evaluation (rules)
source: COBISS
Researchers (24)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  25434  PhD Urban Bren  Chemistry  Researcher  2019 - 2022  369 
2.  34484  PhD Darija Cör Andrejč  Chemical engineering  Researcher  2019 - 2022  93 
3.  28477  PhD Matjaž Finšgar  Chemistry  Researcher  2019 - 2022  417 
4.  23380  PhD Nina Gorišek Miksić  Microbiology and immunology  Researcher  2019 - 2022  111 
5.  52217  Maja Gračnar  Chemical engineering  Researcher  2020 - 2021 
6.  20420  PhD Lidija Gradišnik  Neurobiology  Researcher  2019 - 2022  294 
7.  15751  PhD Radovan Hojs  Metabolic and hormonal disorders  Researcher  2019 - 2022  805 
8.  23194  PhD Iztok Holc  Microbiology and immunology  Researcher  2019 - 2022  312 
9.  02619  PhD Željko Knez  Chemical engineering  Head  2019 - 2022  2,033 
10.  30021  PhD Maša Knez Marevci  Chemical engineering  Researcher  2019 - 2022  320 
11.  21689  PhD Petra Kotnik  Chemical engineering  Researcher  2019 - 2022  157 
12.  02053  PhD Ivan Krajnc  Microbiology and immunology  Researcher  2019 - 2022  615 
13.  37499  PhD Gregor Kravanja  Civil engineering  Researcher  2019 - 2022  111 
14.  00534  PhD Maja Leitgeb  Chemical engineering  Researcher  2019 - 2022  825 
15.  30850  PhD Uroš Maver  Medical sciences  Researcher  2019 - 2022  456 
16.  50675  PhD Marko Milojević  Metabolic and hormonal disorders  Researcher  2019 - 2022  60 
17.  13568  PhD Zoran Novak  Chemical engineering  Researcher  2019 - 2022  249 
18.  15750  PhD Artur Pahor  Microbiology and immunology  Researcher  2019 - 2022  313 
19.  20129  PhD Dušica Pahor  Metabolic and hormonal disorders  Researcher  2019 - 2022  779 
20.  39575  PhD Milica Pantić  Chemical engineering  Researcher  2019 - 2022  51 
21.  37709  Otilija Petek  Biochemistry and molecular biology  Technical associate  2021 - 2022 
22.  55516  Vesna Postružnik  Chemistry  Technical associate  2021 - 2022  20 
23.  21460  PhD Mateja Primožič  Chemical engineering  Researcher  2019 - 2022  361 
24.  52216  PhD Taja Žitek Makoter  Chemical engineering  Researcher  2022  52 
Organisations (3)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0794  University of Maribor, Faculty of Chemistry and Chemical Engineering  Maribor  5089638012  13,182 
2.  0334  University Medical Centre Maribor  Maribor  5054150000  23,101 
3.  2334  University of Maribor, Faculty of Medicine  Maribor  5089638048  15,950 
Abstract
As natural resources such as plant and microorganisms present a plentiful source of unique materials and compounds with a great prospective for applications in different industrial branches, including food industry, medicine and pharmacy. There is a great intention to develop suitable proficient methods for their exploitation. The goal of this project is the isolation of polyphenols, fatty acids, enzymes, natural antioxidants and natural dyes from plant materials and microorganism biomass using sub- and super-critical fluids as environmentally benign processing media. Project proposal is oriented towards examination of the novel obtained extracts in regard of their function in simulated physiological environments, resembling the exposed tissues upon the developed materials proposed use. First, substances of interest will be isolated from both liquids and solid bio-materials. Fractionation of isolated compounds will be achieved by a multi step separation, followed by chromatography using SCFs in order to obtain high purity of isolated substances. The aim of the subsequent stage of the project is formulation of the obtained extracts into specific forms (foams, aerogels, powders …), designed for a specific targeted use. Finally, in vitro tests using human cells will be carried out to proof the bio activity and bio compatibility of the respective isolated substances with targeted cells and/or to show the retained activity of the isolated compounds and/or their mixtures after processing.
Significance for science
The research project entitled “Smart materials for bioapplications” will focus on top-level product engineering at the interface of biotechnology, material science, medicine and chemical engineering. This will efficiently contribute to improvement of quality of life, which is also a basis for sustainable development. It stimulates the mutual linkage of education, research and enterprise and improves the mobility of knowledge, ideas and people within society. “Smart materials” are currently a main stream of research in engineering science, and processes using SC fluids are viewed as one of the key enabling sustainable technologies with almost no impact on the environment. These products will be of high added value and are not obtainable with conventional production processes. Our research will make a significant contribution to fundamental knowledge in the fields of processes and products. The results will be published in journals with high IF or protected by patent applications.  For design of new “smart materials” there is completely new “free scientific field”: to get ideas for new products, to find ideas about possible processes for the product and later realizing the whole work to produce the possible product for commercialization.  The group of researchers participating in the proposed project have world leading knowledge and experience in the development of processes and products and in cooperation with leading researchers from other fields. We will continue to increase the impact of Slovenian science throughout the world.
Significance for the country
The research project entitled “Smart materials for bioapplications” will focus on top-level product engineering at the interface of biotechnology, material science, medicine and chemical engineering. This will efficiently contribute to improvement of quality of life, which is also a basis for sustainable development. It stimulates the mutual linkage of education, research and enterprise and improves the mobility of knowledge, ideas and people within society. “Smart materials” are currently a main stream of research in engineering science, and processes using SC fluids are viewed as one of the key enabling sustainable technologies with almost no impact on the environment. These products will be of high added value and are not obtainable with conventional production processes. Our research will make a significant contribution to fundamental knowledge in the fields of processes and products. The results will be published in journals with high IF or protected by patent applications.  For design of new “smart materials” there is completely new “free scientific field”: to get ideas for new products, to find ideas about possible processes for the product and later realizing the whole work to produce the possible product for commercialization.  The group of researchers participating in the proposed project have world leading knowledge and experience in the development of processes and products and in cooperation with leading researchers from other fields. We will continue to increase the impact of Slovenian science throughout the world.
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Most important socioeconomically and culturally relevant results Interim report
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