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Projects / Programmes source: ARIS

Incidnca primarnega Sjogrenovega sindroma v Sloveniji in primerjava razlicnih diagnosticnih meril (Slovene)

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Research activity

Code Science Field Subfield
3.01.00  Medical sciences  Microbiology and immunology   

Code Science Field
B580  Biomedical sciences  Skeleton, muscle system, rheumatology locomotion 
B680  Biomedical sciences  Public health, epidemiology 
Keywords
Primary Sjögren''s syndrome, diagnostic criteria, incidence of pSS, autoantibodies, virus infections
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (6)
no. Code Name and surname Research area Role Period No. of publications
1.  12154  PhD Maja Hojnik  Microbiology and immunology  Researcher  2000 - 2002  45 
2.  02066  PhD Tatjana Kveder  Microbiology and immunology  Head  2000 - 2002  275 
3.  10080  PhD Dušan Logar  Microbiology and immunology  Researcher  2000 - 2002  128 
4.  16184  PhD Martina Plešivčnik Novljan  Microbiology and immunology  Researcher  2000 - 2002  51 
5.  07180  PhD Blaž Rozman  Microbiology and immunology  Researcher  2000 - 2002  563 
6.  13601  PhD Matija Tomšič  Microbiology and immunology  Researcher  2000 - 2002  764 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,499 
Abstract
SJÖGREN’S syndrome (SS) is a chronic autoimmune disorder which affects the lacrimal and salivary glands, as well as other exocrine glands, leading to functional impairment and mucosal dryness. It is often associated with systemic extraglandular manifestations. SS can occur alone (primary SS) or in association with almost any of the systemic autoimmune rheumatic diseases (secondary SS). The aim of our study is to estimate the incidence of SS in Slovenia. Different diagnostic criteria for SS will be applied and compared. All participants will be asked six standard questions, which are part of EEC diagnostic criteria. Besides to the questionnaire, all patients will be subjected to a Schirmer-I test, Rose Bengal test, fluorescein test, unstimulated salivary flow test, salivary scintigraphy. Immunoserological tests (rheumatoid factors - RF, antinuclear antibodies - ANA, antibodies against different intracellular antigens – anti-ENA) as well as specific antibodies against viruses (HCV and HTLV I) will be performed. If necessary histopathological investigation of the minor salivary glands will be carried out. American authors are convinced that European criteria for pSS are far too lose, thus enabling too many diagnosed pSS patients. Nevertheless, there have been no data published neither about the incidence of pSS nor about any kind of comparison of two different widely used diagnostic criteria.
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