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Projects / Programmes source: ARIS

Vpliv vazodilatatorjev in povecanja volumna krvi na delovanje arteriovenskih fistul za hemodializo po njihovi operativni konstrukciji (Slovene)

Research activity

Code Science Field Subfield
3.06.00  Medical sciences  Cardiovascular system   

Code Science Field
B007  Biomedical sciences  Medicine (human and vertebrates) 
B560  Biomedical sciences  Urology, nephrology 
Keywords
arteriovenous fistula, spasm of artery, vasodilator, duplex sonography
Evaluation (rules)
source: COBISS
Researchers (8)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  01972  PhD Andrej Bren  Cardiovascular system  Researcher  2000 - 2002  507 
2.  10649  PhD Jadranka Buturović-Ponikvar  Cardiovascular system  Researcher  2000 - 2002  1,009 
3.  01975  Andrej Guček  Cardiovascular system  Researcher  2000 - 2002  149 
4.  07766  PhD Staša Kaplan-Pavlovčič  Cardiovascular system  Researcher  2000 - 2002  237 
5.  06203  PhD Marko Malovrh  Cardiovascular system  Head  2000 - 2002  353 
6.  01987  PhD Rafael Ponikvar  Cardiovascular system  Researcher  2000 - 2002  788 
7.  16238  MSc Vladimir Premru  Cardiovascular system  Researcher  2000 - 2002  249 
8.  10579  PhD Alenka Urbančič  Cardiovascular system  Researcher  2000 - 2002  81 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,953 
Abstract
Arteriovenous fistula (AVF) remains the method of choice for hemodialysis access. The most frequent cause for unsuccessful creation or early failure of AVF is low filling volume of artery depending on quality of artery which ability for remodeling after surgery is diminshed. Spasm of artery has also an important role. In the prospective study we plan to rendomize patients with sonographically established signs for changed artery wall and consequently diminished functional alibity in four groups: groupe A where during surgery intravenous vasodilators will be used; group B with local application of vasodilators, together with local infiltration anasthesia; group C with infusion of plasma expander during surgery; group D with non additional intervention. Hypothesis of this study is that use of vasodilators could prevent spasm of artery and minimal ability of little value artery as filling artery for AVF remains preserved. Sometime vasodilator could have unafavorable side effect. Because plasma expander could have positive effect on filling volume of artery, we plan to confirm that such a method could be also effective at this group of patients.
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