International projects source: SICRIS

Neuroactive compounds in Tomatoes and their role in the development of neurodegenerative diseases via the gut-brain axis using a multi-Omics approach

Researchers (1)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  39144  PhD Ana Kovačič  Control and care of the environment  Researcher  2022 - 2024  61 
Growing evidence points to the links between diet, gut, and neurodegenerative diseases (ND). Funded by the Marie Skłodowska-Curie Actions programme, the NeuroTOm project aims to understand the significance of exposure to neuroactive compounds in the diet. Using tomato as a food source, the study will elucidate the role of these chemicals in the gut-brain axis and the ND disease development after digestion. The neuroprotective and neurodisrupting compounds from organic, conventional, and processed tomatoes will be characterised by mass spectrometry. In vitro colon models will be employed to study the fate of these compounds in the gut and identify gut-microbial metabolites and their effect on intestinal epithelium cells.
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