Projects / Programmes source: ARIS

Ecotoxinology and Ecotoxicology

January 1, 1999 - April 30, 2002
Research activity

Code Science Field Subfield
1.03.00  Natural sciences and mathematics  Biology   
1.05.00  Natural sciences and mathematics  Biochemistry and molecular biology   

Code Science Field
B260  Biomedical sciences  Hydrobiology, marine biology, aquatic ecology, limnology 
B230  Biomedical sciences  Microbiology, bacteriology, virology, mycology 
P310  Natural sciences and mathematics  Proteins, enzymology 
B700  Biomedical sciences  Environmental health 
B680  Biomedical sciences  Public health, epidemiology 
B270  Biomedical sciences  Plant ecology 
Evaluation (rules)
source: COBISS
Researchers (8)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  02755  PhD Mihael Bricelj  Biology  Researcher  2001 - 2002  226 
2.  07744  PhD Gorazd Kosi  Biology  Researcher  2001 - 2002  359 
3.  09834  PhD Ciril Krušnik  Biology  Researcher  2001 - 2002  163 
4.  00885  PhD Milan Lovka  Biology  Researcher  2001 - 2002  237 
5.  08089  PhD Jasna Paradiž  Biology  Researcher  2001 - 2002  128 
6.  07736  PhD Bojan Sedmak  Biochemistry and molecular biology  Head  2001 - 2002  232 
7.  18347  Marija Slovnik-Udovč    Researcher  2001 - 2002 
8.  18348  Karmen Stanič    Researcher  2001 - 2002  54 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0105  National Institute of Biology  Ljubljana  5055784  13,390 
Clean and safe water supplies are an essential component of environmental quality and human health. Water quality in reservoirs and other surface water bodies, especially in the north-eastern regions of Slovenia, is unacceptable, because cyanobacterial blooms occur periodically during summer and autumn. The growth of cyanobacteria is a result of elevated nutrient concentration. Nutrients, particularly phosphorous and nitrogen salts, originate from several sources such as run-off of fertilizer, livestock or human wastes. Alternatively, they can be released from bottom sediments, as in the lake Bled. Cyanobacteria produce a broad range of biologically active substances. In addition to relatively harmless contact irritants and endotoxins, they are able to synthesize lethal neurotoxins and hepatotoxins. Microcystins, the most frequent cyanobacterial hepatotoxins, are known to be tumour promoting, tumour inducing and DNA damaging substances. Potentially toxic cyanobacteria have been found in the majority of our water bodies, with the exception of alpine lakes. The inspected blooms have been toxic in over 75% of cases, with a maximum value of 6 mg total microcystins per g of lyophilized cyanobacteria. Qualitative and quantitative evaluations of toxins, have shown the presence of microcystins RR, -YR and -LR. Cyanobacterial blooms also contribute large amounts of organic material to the water. These substances may lead to the formation of tri-halo-methanes after chlorination. Recent findings have demonstrated that microcystins are able to penetrate the waterworks system. Hazard characterization and risk assessment of these toxins in relation to human health requires the identification of possible exposure routes. These include the oral route, respiratory and skin passage exposure, and the circulatory system during haemodialysis. Magnetic resonance imaging (MRI) has been introduced for in vivo evaluation of changes in the liver due to exposure to hepatotoxins.
Views history