Projects / Programmes
Mass spectrometric studies of ions in the gas-phase and in solution
Code |
Science |
Field |
Subfield |
1.04.02 |
Natural sciences and mathematics |
Chemistry |
Structural chemistry |
Code |
Science |
Field |
P351 |
Natural sciences and mathematics |
Structure chemistry |
P300 |
Natural sciences and mathematics |
Analytical chemistry |
ESIand FAB-MS, metastable and colisionally activated dissociations, noncovalent bound complexes, biopolymers, two, three and foure stranded oligonucleotides, host-guest and supramolecular chemistry
Researchers (2)
no. |
Code |
Name and surname |
Research area |
Role |
Period |
No. of publicationsNo. of publications |
1. |
04351 |
PhD Bogdan Kralj |
Chemistry |
Head |
2002 - 2004 |
131 |
2. |
03950 |
PhD Dušan Žigon |
Chemistry |
Researcher |
2002 - 2004 |
169 |
Organisations (1)
no. |
Code |
Research organisation |
City |
Registration number |
No. of publicationsNo. of publications |
1. |
0106 |
Jožef Stefan Institute |
Ljubljana |
5051606000 |
90,742 |
Abstract
Weakly bound noncovalent complexes of organic compounds, e.g. carbohydrates and cations, proteins and metal ions, various protein-protein interacted pairs and particularly the complexes of nucleic acids, such as two, three and four stranded natural and modified oligonucleotides will be studied by "soft", i.e. Fast Atom Bombardment and Electrospray ionization methods.The binding stoichiometry of complexes will be derived from the measurement of molecular mass of the intact complexes and the indiuvidual binding moeties. In some examples, the relative binding affinities will be deduced by using the product ion spectrum (MS/MS) and the kinetic method.