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Projects / Programmes source: ARIS

Mass spectrometric studies of ions in the gas-phase and in solution

Research activity

Code Science Field Subfield
1.04.02  Natural sciences and mathematics  Chemistry  Structural chemistry 

Code Science Field
P351  Natural sciences and mathematics  Structure chemistry 
P300  Natural sciences and mathematics  Analytical chemistry 
Keywords
ESIand FAB-MS, metastable and colisionally activated dissociations, noncovalent bound complexes, biopolymers, two, three and foure stranded oligonucleotides, host-guest and supramolecular chemistry
Evaluation (rules)
source: COBISS
Researchers (2)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  04351  PhD Bogdan Kralj  Chemistry  Head  2002 - 2004  131 
2.  03950  PhD Dušan Žigon  Chemistry  Researcher  2002 - 2004  169 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  90,742 
Abstract
Weakly bound noncovalent complexes of organic compounds, e.g. carbohydrates and cations, proteins and metal ions, various protein-protein interacted pairs and particularly the complexes of nucleic acids, such as two, three and four stranded natural and modified oligonucleotides will be studied by "soft", i.e. Fast Atom Bombardment and Electrospray ionization methods.The binding stoichiometry of complexes will be derived from the measurement of molecular mass of the intact complexes and the indiuvidual binding moeties. In some examples, the relative binding affinities will be deduced by using the product ion spectrum (MS/MS) and the kinetic method.
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