Projects / Programmes source: ARIS

Intraoperative electrophysiological evaluation of compressive lesion of spinal nerve root from herniated disc

Research activity

Code Science Field Subfield
3.03.00  Medical sciences  Neurobiology   

Code Science Field
B640  Biomedical sciences  Neurology, neuropsychology, neurophysiology 
spinal nerve root, neuromonitoring, H-reflex, herniated disc, discectomy, neurosurgery
Evaluation (rules)
source: COBISS
Researchers (3)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  10511  PhD Roman Bošnjak  Neurobiology  Head  2002 - 2003  411 
2.  02710  PhD Vinko Vincenc Dolenc  Neurobiology  Researcher  2002 - 2003  236 
3.  20251  PhD Boštjan Matos  Neurobiology  Researcher  2002 - 2003  44 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  75,631 
Disc herniation produces a compressive lesion od adjacent spinal nerve root (SNR). Routine electrodiagnostic tests evaluate indirect effects of compression of SNR. Surgical manipulation during herniated disc removal may produce additional, mostly transient SNR malfunction, known as "battered root synrome". Monitoring of SNR function during disc removal is possible by continuous direct detection of compound action potential from the SNR. Potentially harmfull manipulation can be recognised and stopped in time. In H-reflex, direct epidural detection of P1 and P2 waves from the root enables selective evalvation of ventral and dorsal root separately. Initial degree of SNR compressive lesion will be intraoperatively evaluated (presence / absence, amplitude, latency, midpotential interval of P1 and P2 waves.) and later correlated to preoperative clinical signs and symptoms, electrodiagnostic tests (EMG). Prognostic value of H reflex could be determined. Monitoring of SNR function during disc removal will enable recognition of harmful manipulations, resulting in refinement of surgical technique and decreasing perioperative morbidity.
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