Projects / Programmes
Contact allergy in modern treatment of disorders caused by chronic venous insufficiency
| Code |
Science |
Field |
Subfield |
| 3.08.00 |
Medical sciences |
Public health (occupational safety) |
|
| Code |
Science |
Field |
| B630 |
Biomedical sciences |
Dermatology, venereology |
contact allergy, skin, chronic venous insufficiency, therapy-side effects
Researchers (5)
| no. |
Code |
Name and surname |
Research area |
Role |
Period |
No. of publicationsNo. of publications |
| 1. |
16307 |
PhD Mateja Dolenc Voljč |
Microbiology and immunology |
Researcher |
2002 - 2004 |
253 |
| 2. |
01174 |
PhD Aleksej Kansky |
Microbiology and immunology |
Researcher |
2002 - 2004 |
223 |
| 3. |
19776 |
PhD Nada Kecelj |
Metabolic and hormonal disorders |
Researcher |
2004 |
189 |
| 4. |
19777 |
Metoda Košiček |
Metabolic and hormonal disorders |
Researcher |
2002 - 2003 |
41 |
| 5. |
11041 |
PhD Tomaž Lunder |
Microbiology and immunology |
Head |
2002 - 2004 |
127 |
Organisations (1)
Abstract
Many reports concerning cases of allergic contact dermatitis due to compounds used in the convcntional treatment of chronic venous insufficiency (CVI), have been published in the literature. However, the problem of contact allergy to the constituents of hidrocoloid dressings has not yet been sistematically investigated. Therefore, our goals in the proposed research project are:
1. to find whether hidrocoloid and other dressings contain irritant or contact sensitizing compounds, which might act upon normal skin or allready inflamed skin in CVI;
2. to evaluate the influence of an eventual skin sensitization or irritation on the process of healing of the ulcer;
3. to identify the causing sensitizing compounds in various products used for treatment, skin cleansing or skin care; besides the analysis using patch testing, an analysis using gas chromatography will be performed;
4. to compare the sensitivity of the skin of the back - where patch tests are usually applied - with the skin in the vicinity of inflamed lesions on the leg;
5. to establish recommendations for development of new products for the treatment of patients with CVI.
We expect that the results of the proposed research project will help to improve current diagnostic procedures and to diminish the exposition of patients with CVI to sensitizing compounds.
