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Projects / Programmes source: ARIS

Activity of Crohn's terminal ileitis: rationalization of diagnostic procedures

Research activity

Code Science Field Subfield
3.06.00  Medical sciences  Cardiovascular system   

Code Science Field
B550  Biomedical sciences  Gastro-enterology 
B725  Biomedical sciences  Diagnostics 
Keywords
terminal ileitis, inflammation activity, Tc-99m-HMPAO-labelled leukocytes, jejunoileography
Evaluation (rules)
source: COBISS
Researchers (8)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  09789  MSc Igor Batagelj  Cardiovascular system  Researcher  2002 - 2004 
2.  10065  PhD Ivan Ferkolj  Metabolic and hormonal disorders  Researcher  2002 - 2004  133 
3.  11714  PhD Marko Grmek  Cardiovascular system  Researcher  2002 - 2004  161 
4.  02930  PhD Vladimir Jevtić  Medical sciences  Researcher  2002 - 2004  223 
5.  03171  PhD Aleksandra Markovič-Predan  Medical sciences  Researcher  2002 - 2004  284 
6.  09070  PhD Metka Milčinski  Cardiovascular system  Head  2002 - 2004  140 
7.  17683  Ivan Slodnjak    Researcher  2002 - 2004  42 
8.  10067  MSc Srečko Štepec  Metabolic and hormonal disorders  Researcher  2002 - 2004  89 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,480 
Abstract
Crohn's terminal ileitis is part of chronic inflammatory bowel disease, connected with relapses and late complications as fistulization or extraluminal infections. Diagnostic procedures in evaluation of inflammatory activity include endoscopic examinations with bioptic confirmation of active disease, scintigraphy with autologous leukocytes and radiographic exams. The sequence of investigations is not predicted, and aim of our study is to optimize the diagnostic algorhytm in evaluation of activity of Crohn's terminal ileitis. Modification of jejunoileography that will allow investigation of small and the beginning of large bowel is proposed and the results will be compared to scintigraphy with autologous leukocytes and endoscopic evaluation. The results will lead to optimization of diagnostic algorhytm and therefore allow early treatment of disease, preventing late complications as fistulizations and abscesses and morbidity connected with this disease.
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