Projects / Programmes source: ARIS

Value of nuclear medicine diagnostic methods in neonates with dilated renal collecting system

Research activity

Code Science Field Subfield
3.05.00  Medical sciences  Human reproduction   

Code Science Field
B145  Biomedical sciences  Nuclear medicine, radiobiology 
B560  Biomedical sciences  Urology, nephrology 
Diuretic renography, obstruction of renal collecting system, neonates, surgery, conservative treatment
Evaluation (rules)
source: COBISS
Researchers (5)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  17679  Jožica Arko    Researcher  2002 - 2004 
2.  09790  PhD Jurij Fettich  Medical sciences  Head  2002 - 2004  297 
3.  11714  PhD Marko Grmek  Medical sciences  Researcher  2002 - 2004  161 
4.  06769  PhD Ciril Grošelj  Medical sciences  Researcher  2002 - 2004  85 
5.  16192  MSc Tomaž Milanez  Medical sciences  Researcher  2002 - 2004  62 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  74,759 
Dilated renal collecting system is found in 0.6 - 0.9% of neonates. Causes of dilatation of the collecting system include also obstruction of collecting system on different levels. Important obstruction can cause irreversible kidney damage. Because of possible impairment of kidney function determination of degree of obstruction is imperative, to decide for surgical or conservative treatment. Opinions on value of diuretic renography to assess obstruction of renal collecting system in neonates in need of surgical treatment are frequently opposed. Some believe that diuretic renography is unreliable, while others try to demonstrate that it can be used to prove or exclude important obstruction of renal collecting system that needs surgical treatment. The aim of the study is to evaluate different parameters obtainable with diuretic renography to determine importance of obstruction of renal collecting system in the neonates. For this purpose the patients will be grouped into two groups: 1) patients with surgically proven obstruction 2) patients with no obstruction on surgery, and patients on conservative treatment with no deterioration of renal function at least six months after initial evaluation. Diagnostic value of different parameters derived from diuretic renography will be determined by appropriate statistical methods to determine prognostic value of these parameters in case of conservative treatment and in situations where surgical management is mandatory.
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