Projects / Programmes
Value of nuclear medicine diagnostic methods in neonates with dilated renal collecting system
Code |
Science |
Field |
Subfield |
3.05.00 |
Medical sciences |
Human reproduction |
|
Code |
Science |
Field |
B145 |
Biomedical sciences |
Nuclear medicine, radiobiology |
B560 |
Biomedical sciences |
Urology, nephrology |
Diuretic renography, obstruction of renal collecting system, neonates, surgery, conservative treatment
Researchers (5)
no. |
Code |
Name and surname |
Research area |
Role |
Period |
No. of publicationsNo. of publications |
1. |
17679 |
Jožica Arko |
|
Researcher |
2002 - 2004 |
0 |
2. |
09790 |
PhD Jurij Fettich |
Medical sciences |
Head |
2002 - 2004 |
297 |
3. |
11714 |
PhD Marko Grmek |
Medical sciences |
Researcher |
2002 - 2004 |
161 |
4. |
06769 |
PhD Ciril Grošelj |
Medical sciences |
Researcher |
2002 - 2004 |
85 |
5. |
16192 |
MSc Tomaž Milanez |
Medical sciences |
Researcher |
2002 - 2004 |
62 |
Organisations (1)
Abstract
Dilated renal collecting system is found in 0.6 - 0.9% of neonates. Causes of dilatation of the collecting system include also obstruction of collecting system on different levels. Important obstruction can cause irreversible kidney damage. Because of possible impairment of kidney function determination of degree of obstruction is imperative, to decide for surgical or conservative treatment.
Opinions on value of diuretic renography to assess obstruction of renal collecting system in neonates in need of surgical treatment are frequently opposed. Some believe that diuretic renography is unreliable, while others try to demonstrate that it can be used to prove or exclude important obstruction of renal collecting system that needs surgical treatment.
The aim of the study is to evaluate different parameters obtainable with diuretic renography to determine importance of obstruction of renal collecting system in the neonates.
For this purpose the patients will be grouped into two groups:
1) patients with surgically proven obstruction
2) patients with no obstruction on surgery, and patients on conservative treatment with no deterioration of renal function at least six months after initial evaluation.
Diagnostic value of different parameters derived from diuretic renography will be determined by appropriate statistical methods to determine prognostic value of these parameters in case of conservative treatment and in situations where surgical management is mandatory.