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Projects / Programmes source: ARIS

Influence of higher iodine prophylaxis on the prevalence of goitre in Slovenia

Research activity

Code Science Field Subfield
3.05.00  Medical sciences  Human reproduction   

Code Science Field
B480  Biomedical sciences  Endocrinology, secreting systems, diabetology 
Keywords
thyroid gland, goitre, iodine prophylaxis
Evaluation (rules)
source: COBISS
Researchers (6)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  01889  Jurij Avčin    Researcher  2002 - 2004  18 
2.  11039  PhD Simona Gaberšček  Cardiovascular system  Researcher  2002 - 2004  453 
3.  15706  PhD Tanja Gmeiner  Pharmacy  Researcher  2002 - 2004  147 
4.  01900  PhD Sergej Hojker  Human reproduction  Head  2002 - 2004  314 
5.  11744  PhD Edvard Pirnat  Microbiology and immunology  Researcher  2002 - 2004  216 
6.  20484  PhD Katja Zaletel  Metabolic and hormonal disorders  Researcher  2002 - 2004  422 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,680 
Abstract
Iodine is an element, essential for the synthesis of thyroid hormones and for the regulation of thyroid growth. The most important source of iodine in our nutrition is iodized salt. Most estimates of the dietary supply of iodine are based on the measurment of the excretion of iodine in urine. Higher incidence of goitre and toxic adenmas are the consequences of the iodine deficiency in daily food. There are still many countries with iodine deficiency. The state of iodine deficiency has important consequences from a public health point of view, therefore WHO tends to eliminate the problem. Results of our previous epidemiolological studies have shown Slovenia has an area of mild iodine deficiency. A study, wich included in years between 1992 and 1994 a larger group of thirteen-years old children showed palpatory detectable goitre in more than 70% of children, while there iodine excretion level was too low. Until 1999 was our salt supplemented with 10 mg of KI (potasium iodine) per kg. In 1999 higher supplemented with 25 mg of KI per kg of salt was started. The scope of our epidemiolological study is to evaluate the succes of higher iodine supplementation; The same studies were performed in other countries, where iodine supplementation was changed. In selected population, the size of thyroid gland will be determined by palpation and by ultrasound measurments, additionaly, urinary iodine exceretion will be measured. According to the WHO and ICCIDD (International Council for Control of Iodine Deficiency Disorders) recommendations, the adequacy of the iodine supplementation in Slovenia will be established. If inspite of adequate iodine supplementation regions of higher incidence of goitre will be found, other causes for gland enlargement will be searched.
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