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Projects / Programmes source: ARIS

The role of fungi in the pathogenesis of the chronic posttraumatic osteitis

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Research activity

Code Science Field Subfield
3.01.00  Medical sciences  Microbiology and immunology   

Code Science Field
B510  Biomedical sciences  Infections 
Keywords
osteitis, fungi, trauma, antimycotics
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (8)
no. Code Name and surname Research area Role Period No. of publications
1.  02497  PhD Andrej Baraga  Neurobiology  Researcher  2002 - 2004  56 
2.  08312  PhD Bojana Beovič  Microbiology and immunology  Head  2002 - 2004  462 
3.  10802  PhD Matej Cimerman  Neurobiology  Researcher  2002 - 2004  263 
4.  14392  PhD Vojka Gorjup  Cardiovascular system  Researcher  2002  201 
5.  05935  PhD Nina Gunde-Cimerman  Biotechnology  Researcher  2002 - 2004  1,261 
6.  13300  PhD Matjaž Jereb  Microbiology and immunology  Researcher  2002 - 2004  251 
7.  11351  PhD Simona Kržišnik Zorman  Cardiovascular system  Researcher  2002  81 
8.  16103  PhD Polona Zalar  Microbiology and immunology  Researcher  2002 - 2004  462 
Organisations (2)
no. Code Research organisation City Registration number No. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,480 
2.  0481  University of Ljubljana, Biotechnical Faculty  Ljubljana  1626914  66,844 
Abstract
Chronic posttraumatic osteitis is a difficult-to-treat and debilitating complication of trauma. The part of the bone involved in the chronic inflammatory process is ishaemic and infected by bacteria. The antibiotic treatment is complicated for pharamacokinetic reasons and altered metabolism of the bacteria in the necrotic bone tissue. Some recent reports suggest the role of fungi in the bone inflammatory process. Since fungi are not influenced by antibiotics, the presence of the fungal infection may cause the treatment failure. In a proposed research project we will try to prove the hypothesis of the fungi as pathogens in the chronic posttraumatic osteitis by isolating them from the inflammed bone tissue. The influence of antimycotics on the course of the disease in patients infected by fungi will be observed.
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