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Projects / Programmes source: ARIS

Calcium and cAMP “in vivo” and their influence on intracellular pH in Aspergillus niger

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Research activity

Code Science Field Subfield
4.06.00  Biotechnical sciences  Biotechnology   

Code Science Field
T490  Technological sciences  Biotechnology 
T360  Technological sciences  Biochemical technology 
B230  Biomedical sciences  Microbiology, bacteriology, virology, mycology 
B220  Biomedical sciences  Genetics, cytogenetics 
Keywords
cAMP, calcium, signal transduction, fungi, Aspergillus niger, intracellular pH
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (3)
no. Code Name and surname Research area Role Period No. of publications
1.  14360  PhD Mojca Benčina  Biotechnology  Head  2002 - 2004  392 
2.  00385  PhD Nada Kraševec  Biotechnology  Researcher  2002 - 2004  215 
3.  17028  PhD Aleš Novak  Law  Researcher  2001 - 2002  263 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  0104  National Institute of Chemistry  Ljubljana  5051592000  21,007 
Abstract
In biotechnologically important fungus Aspergillus niger, plasma membrane H+-ATPase plays a significant role in controlling intracellular pH and global regulation of metabolism. The activity of H+-ATPase is regulated by calcium/calmodulin-dependent protein kinase phosphorylation. After cloning and characterisation of calcium/calmodulin-dependent protein kinase, its involvement in signal transduction will be determined. Cyclic-AMP and phospholipid signal transduction cross talk will be determined using a novel recombinant system for detection of cytosolic free calcium ions and cAMP "in vivo" in A. niger.
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