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Projects / Programmes source: ARIS

Molecular markers in the early and late events in cervical carcinogenesis

Research activity

Code Science Field Subfield
3.05.00  Medical sciences  Human reproduction   

Code Science Field
B200  Biomedical sciences  Cytology, oncology, cancerology 
B570  Biomedical sciences  Obstetrics, gynaecology, andrology, reproduction, sexuality 
Keywords
molecular markers, early and late events, cervical carcinogenesis
Evaluation (rules)
source: COBISS
Researchers (13)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  13314  PhD Matija Barbič  Human reproduction  Researcher  2003 - 2005  170 
2.  09176  PhD Jože Bertole  Human reproduction  Researcher  2003 - 2005  56 
3.  08906  PhD Mojca Eržen  Human reproduction  Head  2003 - 2005  116 
4.  06970  PhD Borut Kobal  Human reproduction  Researcher  2003 - 2005  420 
5.  20875  Darja Kopač  Human reproduction  Researcher  2003 - 2005 
6.  06171  PhD Adolf Lukanovič  Human reproduction  Researcher  2003 - 2005  781 
7.  13515  PhD Leon Meglič  Human reproduction  Researcher  2003 - 2005  151 
8.  06173  Andrej Možina  Human reproduction  Researcher  2003 - 2005  172 
9.  06998  Andrej Omahen  Human reproduction  Researcher  2003 - 2005  84 
10.  02355  PhD Stelio Rakar  Human reproduction  Researcher  2003 - 2005  272 
11.  17650  Jelka Simončič    Technical associate  2003 - 2005 
12.  07183  Jasna Šinkovec  Human reproduction  Researcher  2003 - 2005  134 
13.  20952  Jožefa Škof    Technical associate  2003 - 2005 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,764 
Abstract
The key objective is to gain additional information about the molecular mechanisms regulating the pathogenesis and natural history of early (CIN lesions and microinvasive carcinoma) and late events (stage IB or more) in the presence and absence of HPV. At best, some of the tested biological factors might prove to be valuable prognostic markers for the outcome of CIN lesions (progressive/regressive) and for the clinical course and survival of patients with invasive cervical carcinoma. To elucidate the mechanisms underlying this divergent clinical course and histopathological parameters both molecular biological and IHC techniques will be used to complete these analyses.
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