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Projects / Programmes source: ARIS

Influence of statins on cancer growth

Research activity

Code Science Field Subfield
3.04.00  Medical sciences  Oncology   

Code Science Field
B200  Biomedical sciences  Cytology, oncology, cancerology 
Keywords
lung cancer, cell culture, cholesterol, simvastatin
Evaluation (rules)
source: COBISS
Researchers (9)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  08827  MSc Marko Bitenc  Oncology  Researcher  2003 - 2005  140 
2.  02005  PhD Janez Eržen  Oncology  Researcher  2003 - 2005  188 
3.  06759  Jože Jerman  Oncology  Researcher  2003 - 2005  61 
4.  14642  PhD Alenka Mavri  Cardiovascular system  Researcher  2003 - 2005  222 
5.  14574  PhD Mojca Urška Mikac  Physics  Researcher  2003 - 2005  151 
6.  23786  PhD Janez Ravnik  Neurobiology  Researcher  2003 - 2005  229 
7.  23787  Maja Ravnik  Oncology  Researcher  2003 - 2005  103 
8.  09763  PhD Mihael Sok  Oncology  Head  2003 - 2005  221 
9.  01119  PhD Marjeta Šentjurc  Biochemistry and molecular biology  Researcher  2003 - 2005  511 
Organisations (3)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  91,836 
2.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,892 
3.  0334  University Medical Centre Maribor  Maribor  5054150000  23,071 
Abstract
It is known that lung cancer is associated with hypocholesterolemia and that the survival of patients with lung cancer is inversely related to concentration of serum cholesterol. With our research we try to explaine different relationships between serum cholesterol and lung cancer. We will compare behaviour of lung cancer cells in vitro under different growing conditions. The influence of cholesterol lowering drugs (statins) will be investigated. At the same time we will explore the influence of sinchrone terapy with statins and citostatics on the cancer cells. The results of our survey will help to answer the question about use of anticholesterol treatment in cancer patients.
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