Projects / Programmes source: ARIS

Transcription of anorexia candidate genes and an attempt of elaborating DNA microarray

Research activity

Code Science Field Subfield
3.08.00  Medical sciences  Public health (occupational safety)   

Code Science Field
B007  Biomedical sciences  Medicine (human and vertebrates) 
B650  Biomedical sciences  Psychiatry, clinical psychology, psychosomatics 
B220  Biomedical sciences  Genetics, cytogenetics 
eating disorders; anorexia; candidate genes; gene expression; RT-PCR; suubtractive hybridization; DNA micor-arrays; transcriptome
Evaluation (rules)
source: COBISS
Researchers (4)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  21039  PhD Mojca Gabrovšek  Biochemistry and molecular biology  Researcher  2003 - 2005 
2.  18529  Dubravka Germ    Technical associate  2003 - 2005 
3.  06135  PhD Radovan Komel  Biochemistry and molecular biology  Head  2003 - 2005  1,053 
4.  14305  PhD Mirjana Liović  Metabolic and hormonal disorders  Researcher  2003 - 2005  146 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  45,408 
Anorexia nervosa is a severe eating disorder which affects about 0.1% of women. It is rare in males. Its aetiology is still unknown, but current evidence points to both psychosocial factors and the role of genes. The genes involved might influence response to stress, endocrine function, metabolic rate, personality and aspects of apetite, all of which have been impicated in this polygenic and multifactorial disorder. As the members of the EC Framework Five Consortium 'Factors in Healthy Eating' in an European polycentic study we have inbestigated 12 candidate genes, and the results will be published in a series of papers until the end of the year 2003. The Consortium applied EoI (Expression of Interest) for the EC Framework Six, which has been accepted as one of the first priorities within the FW6 and therefore opens chance for a membership in the future FW6 integrative project. In the EoI for this integrative project our laboratory was included as a centre for elaboration of DNA microarrays and investigation of systemic expression of the anorexia candidate genes - which is also the aim of this project application.
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