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Projects / Programmes source: ARIS

Molecular Epidemiology of Tuberculosis in Slovenia

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Research activity

Code Science Field Subfield
3.08.00  Medical sciences  Public health (occupational safety)   

Code Science Field
B680  Biomedical sciences  Public health, epidemiology 
B230  Biomedical sciences  Microbiology, bacteriology, virology, mycology 
Keywords
Tuberculosis, molecular typing, epidemiology, Mycobacterium tuberculosis, transmission
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (4)
no. Code Name and surname Research area Role Period No. of publications
1.  15778  Damijan Eržen  Public health (occupational safety)  Researcher  2003 - 2005  198 
2.  06630  PhD Pika Meško Brguljan  Biochemistry and molecular biology  Researcher  2003 - 2005  347 
3.  09808  PhD Jurij Šorli  Cardiovascular system  Head  2003 - 2005  354 
4.  07627  PhD Marija Žolnir-Dovč  Microbiology and immunology  Researcher  2003 - 2005  303 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  1613  University Clinic of Respiratory and Allergic Diseases  Golnik  1190997  7,125 
Abstract
Tuberculosis is infectious disease, transfered from patient to patient through the air and is as such poorly traceable. The purpose of this project is to perform a systematic molecular typing of tubercle bacilli for the period of several years for all patients in the whole country, and to use the results to characterize the most common pathways of transfer of tubercle bacilli among tuberculosis patients in Slovenia. The project will include the existing programme of management of tuberculosis patients in Slovenia what will help in understanding and identification of critical points of transfer of the disease. Distinct clinical problems will be addressed with the analysis in the project ie. microepidemies at home and in various institutions, endogeneus reactivation of the disease versus exogeneus reinfection with another strain of tubercle bacilli, frequency and mechanisms of diagnostic errors. On the basis of the results the existing protocol of mangement of tuberculosis patients will be expanded and modified to effecitvely include the results of molecular epidemiology of tuberculosis. With routine utilization of relevant epidemiological data together with the data of molecular typing and consecutive measures an accelerated decline of tuberculosis in Slovenia would be achieved.
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