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Projects / Programmes source: ARIS

Molecular diagnosis of atypical pneumonias

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Research activity

Code Science Field Subfield
3.01.00  Medical sciences  Microbiology and immunology   

Code Science Field
B540  Biomedical sciences  Respiratory system 
Keywords
pneumonia, Mycoplasma pneumoniae, Chlamydia pneumonia, polymerase chain reaction
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (5)
no. Code Name and surname Research area Role Period No. of publications
1.  15778  Damijan Eržen  Public health (occupational safety)  Researcher  2003 - 2005  0 
2.  20179  Peter Kecelj  Oncology  Researcher  2003 - 2005  0 
3.  22807  PhD Peter Korošec  Microbiology and immunology  Researcher  2003 - 2005  0 
4.  00288  PhD Ema Mušič  Microbiology and immunology  Head  2003 - 2005  0 
5.  22806  PhD Viktorija Tomič  Microbiology and immunology  Researcher  2003 - 2005  0 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  1613  University Clinic of Respiratory and Allergic Diseases  Golnik  1190997  0 
Abstract
Choice of antibiotics for therapy of atypical pneumonia is usually empirical since standard laboratory methods are relatively insensitive and/or slow to perform. Antimicrobial agent prescribed is usually of a too wide spectrum or we use a combination therapy of two antibiotics. Detection of Mycoplasma pneumoniae and Chlamydia pneumoniae as etiologic agents of pneumonia is very important since it determines the choice of a specific class of antimicrobial agents. At present diagnosis of infection with atypical bacteria is made by serological testing which gives results too late to be used in patient management in acute stage of the disease. Bacterial isolation methods are also slow and technically very demanding so they are not used routinelly. With employment of molecular biology techniques (PCR - polymerase chain reaction) we would like to be able to execute a speedy diagnosis of atypical pathogens. At the same time we would like to get an usefull tool to evaluate the diagnostic value of commercial serological tests.
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