Projects / Programmes source: ARIS

Genetic studies of bacterial acetate resistance and its applications in microbiological systems

Research activity

Code Science Field Subfield
4.06.00  Biotechnical sciences  Biotechnology   

Code Science Field
T490  Technological sciences  Biotechnology 
microorganisms, stress response, acetate resistance, acetic acid bacteria
Evaluation (rules)
source: COBISS
Researchers (3)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  11790  PhD Tjaša Griessler Bulc  Biology  Researcher  2003 - 2005  499 
2.  14279  PhD Janja Trček  Biotechnology  Head  2003 - 2005  185 
3.  19043  PhD Maja Zupančič Justin  Control and care of the environment  Junior researcher  2003 - 2005  349 
Organisations (1)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  1509  Limnos, podjetje za aplikativno ekologijo, d.o.o. (Slovene)  Brezovica pri Ljubljani  5834112  209 
The mechanisms that bacteria have evolved for acetate resistance are probably similar to those that the bacteria have evolved for tolerance against other weak organic acids, such as lactic, propionic and citric acid. Since the mentioned acids are often the end- or by-products in many biotechnological processes, it is very important that the microorganisms involved in the process, tolerate their high concentrations. Studies of the genetic basis of the acetate-resistance are therefore not only a valuable step in direction of understanding the response of bacteria to acetate but also more generally, to inhibitory concentrations of metabolic by-products. The objectives of the proposed project are therefore: (i) to elucidate the molecular basis of acetate tolerance, (ii) to isolate and identify genes important for naturally acetate-resistant bacteria, (iii) to investigate the applications of these genes to increase acetate production by acetic acid bacteria and (iv) to confer higher acetate tolerance also to other industrially important bacteria.
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