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Projects / Programmes source: ARIS

Identification and remediation of pharmaceutical residues in effluent and surface waters

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Research activity

Code Science Field Subfield
1.08.00  Natural sciences and mathematics  Control and care of the environment   

Code Science Field
P305  Natural sciences and mathematics  Environmental chemistry 
B260  Biomedical sciences  Hydrobiology, marine biology, aquatic ecology, limnology 
Keywords
pharmaceutical substances, residues, NSAIDs, gas chromatography, mass spectrometry, derivatisation, solid phase extraction, waste waters, surface waters, treatment, waste water treatment plant
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (7)
no. Code Name and surname Research area Role Period No. of publications
1.  12315  PhD Ester Heath  Control and care of the environment  Head  2004 - 2007  589 
2.  08314  PhD Radmila Milačič  Control and care of the environment  Researcher  2004 - 2007  792 
3.  11279  PhD Nives Ogrinc  Control and care of the environment  Researcher  2004 - 2007  1,120 
4.  08946  Silva Perko    Technical associate  2004 - 2007  51 
5.  05258  PhD Arkadije Popović  Chemistry  Researcher  2004 - 2007  81 
6.  18359  PhD Janez Ščančar  Control and care of the environment  Researcher  2004 - 2007  668 
7.  03950  PhD Dušan Žigon  Chemistry  Researcher  2004 - 2007  167 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  88,443 
Abstract
Pharmacologically active substances are used annually to treat human and animal illnesses. They can enter in the water ecosystem via waste and surface waters. Some of these substances are excreted as unmetabolised or as active metabolites. Therefor determination, fate and behavior of pharmaceutical substances in the environment (transport and degradation processes) are essential. The scope of our project is the quantitative determination of pharmaceutical residues in natural and waste waters in ng/L scale, to estimate extent of pollution in Slovenia and test different treatment strategies for these residues at the pilot scale and in active Slovenia wastewater treatment plants. Analytical procedure for the determination of these substances in waters will be based on solid phase extraction, gas chromatography and mass spectrometry (GC-MS, HR MS, MS-MS). The developed procedure will be tested with artificially prepared waste waters. Pharmacologically active substances involved in our study will be chosen according to their wide application in Slovenia and main financing organisation interests, for example: NSAIDs: Ibuprofen, Ketoprofen, Diclofenac, Naproxen. Analytical procedures will be used to test real samples. Results from this part of study will be used to estimate the extent of pharmaceutical residues in the aquatic environment in Slovene. The second stage of this project is concerned with the (bio)degradation and reduction in pilot and active wastewater treatment plants. The rest of financing organisations (waste water treatment plants with mechanical and/or biological treatment or reverse osmoses) will play an important role in this part of research. In parallel we will be studying wastewater treatment on pilot treatment plant with different treating applications: membrane flittering, UV degradation, coagulation, and filtration.
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