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Projects / Programmes source: ARIS

Role of cysteine cathepsins as immunomodulators in rheumatoid arthritis

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Research activity

Code Science Field Subfield
1.05.00  Natural sciences and mathematics  Biochemistry and molecular biology   

Code Science Field
B000  Biomedical sciences   
Keywords
Rheumatoid arthritis, immune response, chemokines, cytokines, cysteine cathepsins, macrophages
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (2)
no. Code Name and surname Research area Role Period No. of publications
1.  21560  PhD Urška Repnik  Microbiology and immunology  Researcher  2006 - 2007  149 
2.  07561  PhD Boris Turk  Biochemistry and molecular biology  Head  2006 - 2007  1,037 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  90,664 
Abstract
Rheumatoid arthritis is a chronic inflammatory disease, which affects 0.5-1 % of adult population in the industrial world resulting in a diminished quality of life. A cellular model to study the molecular mechanism of rheumatoid arthritis progression will be established. The role of cysteine cathepsins as possible immunomodulators will be investigated in this model system, including chemokine processing. Using functional genomics analysis differentially expressed genes in rheumatoid arthritis will be identified.
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