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Projects / Programmes source: ARIS

Problematika infekcij z virusom herpes simplex (HSV) v slovenski populaciji glede na genitalne manifestacije (Slovene)

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Research activity

Code Science Field Subfield
3.01.00  Medical sciences  Microbiology and immunology   
Keywords
genital herpes, antibodies to herpes simplex virus (HSV) type 1 and type 2, epidemiologic study
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (8)
no. Code Name and surname Research area Role Period No. of publications
1.  18390  Majda Jeruc    Researcher  1998 - 1999  0 
2.  05381  PhD Darja Keše  Microbiology and immunology  Researcher  1998 - 1999  268 
3.  02007  Milena Kristan  Public health (occupational safety)  Researcher  1998 - 1999  9 
4.  03172  PhD Jožefa Marin  Microbiology and immunology  Researcher  1998 - 1999  237 
5.  02006  Marta Penko-Rode  Microbiology and immunology  Researcher  1998 - 1999  12 
6.  08993  PhD Marko Potočnik  Public health (occupational safety)  Researcher  1998 - 1999  252 
7.  16320  Mirjam Rogl Butina  Microbiology and immunology  Researcher  1998 - 1999  113 
8.  12177  PhD Eda Vrtačnik-Bokal  Human reproduction  Researcher  1998 - 1999  594 
Organisations (2)
no. Code Research organisation City Registration number No. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,381 
2.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  48,203 
Abstract
We intend to evaluate the epidemiology of herpes simplex type1 and type 2 in Slovene population. Therefore two groups were formed; in the first (the STD group) are patients treated at the outpatient clinics for sexually transmitted diseases (STDs) in Ljubljana and Maribor. The second group (the control group) is formed from persons whose eventual disease is in no way connected with sexually transmitted infections and who have a negative history of sexually tramsmitted deseases. The control group is adjusted to the STD group regarding the age and sex of the attendees. 221 sera were tested and 200 results were statistically analysed - 100 from each group. Blood samples were collected and tested at the Institute for Microbiology and Immunology of Medical Faculty (MF) Ljubljana. For detection of IgG antibodies against HSV type 1 the Behring Enzygnost anti HSV (IgG) reagents and for detection of antibodies against HSV type 2 Virotech ELISA Testkit Herpes simplex 2 (for IgG detection) were used. The following results were obtained: the prevalence of IgG antibodies against HSV type 1 was 91 % in the STD group and 82 % in the control group. The prevalence of IgG antibodies against HSV type 2 was 69 % in the STD group and 57 % in the control group. High titers of antibodies to HSV type 2 in both groups and especially the absence of statistically significant difference between them induced us to reexamine a number of sera with the ELISA type specific test for HSV type 2 from the Gull Laboratories. At the reexamination essentially lower percentage of anti HSV type 2 positive sera were obtained: in the STD group roughly 17 % and in the control group only a few percents.
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