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Projects / Programmes source: ARIS

Biochemical and genetical markers of microvascular (diabetic retinopathy and diabetic nephropathy) and macrovascular complications (coronary artery disease) and in type 2 diabetes

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Research activity

Code Science Field Subfield
3.07.00  Medical sciences  Metabolic and hormonal disorders   

Code Science Field
B480  Biomedical sciences  Endocrinology, secreting systems, diabetology 
B350  Biomedical sciences  Development biology, growth (animal), ontogeny, embryology 
Keywords
type 2 diabetes; microvascular complications of diabetes; diabtic retinopathy; diabetic nephropathy; genetic markers; biochemical markers; coronary artery disease; myocardial infarction
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (11)
no. Code Name and surname Research area Role Period No. of publications
1.  28259  PhD Armin Alibegović  Cardiovascular system  Researcher  2008  58 
2.  20471  Dejan Bregar    Technical associate  2008 - 2011  10 
3.  28348  PhD Ines Cilenšek  Cardiovascular system  Junior researcher  2008 - 2011  45 
4.  26267  Manja Dolinar    Technical associate  2008  0 
5.  20707  PhD Mojca Globočnik Petrovič  Neurobiology  Researcher  2008 - 2011  260 
6.  18265  Cirila Gros    Technical associate  2010  0 
7.  30148  Marjeta Kuhar    Technical associate  2009 - 2011  0 
8.  29610  PhD Mitja Letonja  Cardiovascular system  Researcher  2008 - 2011  55 
9.  31962  PhD Jovana Nikolajević-Starčev.  Cardiovascular system  Junior researcher  2010 - 2011  45 
10.  11252  PhD Danijel Petrovič  Cardiovascular system  Head  2008 - 2011  318 
11.  23769  Matej Završnik  Metabolic and hormonal disorders  Researcher  2008 - 2011  112 
Organisations (3)
no. Code Research organisation City Registration number No. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  78,447 
2.  0334  University Medical Centre Maribor  Maribor  5054150000  23,263 
3.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  49,127 
Abstract
Biochemical and genetical markers of microvascular (diabetic retinopathy and diabetic nephropathy) and macrovascular complications (coronary artery disease) and in type 2 diabetes
Significance for science
The results help us to understand molecular and genetic mechanisms of microvascular (diabetic retinopathy and nephropathy- DR, diabetic nephropathy - DN) and macrovascular (myocardial infarction - MI and atherosclerosis of carotid arteries) complications of type 2 diabetes. In retrospective cross-sectional case-control study new candidate genes for micro- and macrovascular complications of type 2 diabetes were found. Genetic markers of micro- and macrovascular complications of type 2 diabetes help us to identify patients at high risk for those complications of type 2 diabetes (micro- and macrovascular complications). Those subjects should be treated even more vigurously, and should be checked even more often in comparison to those who are not exposed to such a high risk to develop complications. With the implementation of our findings we will be able to identify pts at high risk, and to prevent the development of complications of type 2 diabetes (primary and secondary prevention). Moreover, these findings will help us to find new drugs for treatment/prevention of complications of type 2 diabetes.
Significance for the country
The results help us to understand molecular and genetic mechanisms of microvascular (diabetic retinopathy - DR, diabetic nephropathy - DN) and macrovascular (myocardial infarction - MI and atherosclerosis of carotid arteries) complications of type 2 diabetes. In retrospective cross-sectional case-control study new candidate genes for micro- and macrovascular complications of type 2 diabetes were found. Genetic markers of micro- and macrovascular complications of type 2 diabetes help us to identify patients at high risk for those complications of type 2 diabetes (micro- and macrovascular complications). Those subjects should be treated even more vigurously, and should be checked even more often in comparison to those who are not exposed to such a high risk to develop complications. With the implementation of our findings we will be able to identify pts at high risk, and to prevent the development of complications of type 2 diabetes (primary and secondary prevention). Moreover, these findings will help us to find new drugs for treatment/prevention of complications of type 2 diabetes.
Most important scientific results Annual report 2008, 2009, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2008, 2009, final report, complete report on dLib.si
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