Projects / Programmes source: ARIS

Mapping in tokamak walls and inside biological cells

Research activity

Code Science Field Subfield
7.00.00  Interdisciplinary research     

Code Science Field
P230  Natural sciences and mathematics  Atomic and molecular physics 
Fusion, hydrogen, plasma, tokamak, deuterium, cell, physiology, X-ray specrtrum, proton beam, tissue, microelements, heavy metals
Evaluation (rules)
source: COBISS
Researchers (7)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  15648  PhD Matjaž Kavčič  Physics  Researcher  2008 - 2011  241 
2.  20428  PhD Matevž Likar  Biology  Researcher  2008 - 2011  281 
3.  12314  PhD Primož Pelicon  Physics  Head  2008 - 2011  583 
4.  25512  PhD Paula Pongrac  Biology  Researcher  2009 - 2011  286 
5.  12013  PhD Marjana Regvar  Biology  Researcher  2008 - 2011  537 
6.  05591  MSc Zdravko Rupnik  Physics  Researcher  2008 - 2011  182 
7.  21623  PhD Katarina Vogel Mikuš  Biology  Researcher  2008 - 2011  615 
Organisations (2)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  90,058 
2.  0481  University of Ljubljana, Biotechnical Faculty  Ljubljana  1626914  66,604 
High-energy focused ion beam is formed by stron magnetic quadrupole lenses. Lateral elemental and isotopic maps are measured by controlled beam scanning over selected regions of specimen, resulting in a lateral resolution determined by beam size. Elemental mapping is based on detection of X-rays excited by focused proton beam. Focused ion beam of 3He isotope is used to excite nuclear reaction D(3He,p)4He, which is used to determine deuterium concentration in the sample. The project proposed includes: 1. Development of detection method and research of fuel retention in tokamak walls with high lateral resolution, based on deuterium mapping in materials exposed to tokamak plasma in controlled fusion experiments. 2. Development of frozen hydrated sample preparation and handling, as well as research with proton microbeam on frozen hydrated samples, which will feature unperturbed morphology at both tissue and sub-cell resolution level, including lateral distribution of major elements and microelements.
Significance for science
In the frame of the Project, we upgraded the measuring station with high-energy focused ion beam using own original ideas and construction approaches and at three fields we achieved level of world excellence: - we constructed and put in operation in 2010 the only existing dedicated confocal PIXE setup, -we upgraded the sample manipulation with the system for transfer and preservation of the tissue in the frozen hydrated state during the micro-PIXE spectroscopy at the temperature below -130 degree Centigrade. - micro-NRA detection setup for work with 3He microbeam Using this non-standard research methods, not available as commercially obtainable instruments, we are in a position to perform research at the many interdisciplinary fields, including biomedicine, fusion and environment. Micro-PIXE with dedicated tissue preparation protocols is enabling the unique research of the physiological processes in life organisms, which is not possible or difficult with classical research methods in biomedicine. It provides quantitative elemental mapping of the tissue and simultaneous determination of distribution of physiological elements, microelements and heavy metals in the tissue. Special added value is introduced to the applicability of the method within the Project reported by the instrumentation and protocols for frozen hydrated tissue handling, as it provides the best approximation to the in-vivo state and enables the determination of elemental maps at the sub-cellular level. With micro-NRA, developed within the project, we manage to perform measurements, which are not feasible with standard NRA method, more widely available related method with 1 mm beam diameter. Excellent lateral resolution of the micro-NRA method enables detailed insight in the processes in the exposed surface of the tokamak wall materials. We studied in detail the role of surface micro-topography on the fuel retention and investigated the processes in the castellated gaps, which contributes significantly to the knowledge required for the operation of new fusion device ITER.
Significance for the country
The Project enabled high-quality research at the field of biomedicine with elemental mapping of biological tissue. The improvements in the frame of the project resulted in the international recognition of the Centre and the JSI at the international level. The recent improvements at the microprobe within the Project at the field of frozen tissue technology will even increase the already present high beamtime demand among the international community. In this way the high-energy focused ion beam at the ion accelerator of JSI became one of the few national large instrumental research installations, which enables the access domestic as well as international researchers based on the approved research proposal. In parallel with the handling and in-house development of the high-energy focused beam technology, new industrial applications and ideas for new hi-tec products are emerging as »spin-offs« (Industrial Project DPP in collaboration with Instrumentation technologies, d.o.o., Solkan).).
Most important scientific results Annual report 2008, 2009, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2008, 2009, final report, complete report on dLib.si
Views history