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Projects / Programmes source: ARIS

Bioinorganic and bioorganic chemistry

Periods
Research activity

Code Science Field Subfield
1.04.00  Natural sciences and mathematics  Chemistry   

Code Science Field
P360  Natural sciences and mathematics  Inorganic chemistry 

Code Science Field
1.04  Natural Sciences  Chemical sciences 
Keywords
bioactive metal complexes, metals in the environment, materials for biosensors, biomimetics, fluorination, iodination, perfluoro solvents
Evaluation (rules)
source: COBISS
Researchers (26)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  32145  PhD Leon Bedrač  Chemistry  Junior researcher  2011 - 2013  19 
2.  03440  PhD Nataša Bukovec  Chemistry  Researcher  2009 - 2013  351 
3.  03439  PhD Peter Bukovec  Chemistry  Head  2009 - 2013  544 
4.  16256  PhD Romana Cerc Korošec  Chemistry  Researcher  2009 - 2013  348 
5.  29927  PhD Ksenija Cer Kerčmar  Chemistry  Junior researcher  2009 - 2013  14 
6.  19050  Damjan Erčulj    Technical associate  2009 - 2013 
7.  31950  PhD Petra Galer  Chemistry  Junior researcher  2009 - 2013  27 
8.  12075  PhD Sabina Grabner  Chemistry  Researcher  2009 - 2013  49 
9.  14680  PhD Jernej Iskra  Chemistry  Researcher  2009 - 2013  401 
10.  19177  PhD Marjan Jereb  Chemistry  Researcher  2009 - 2013  160 
11.  14517  PhD Berta Košmrlj  Chemistry  Researcher  2011 - 2013  98 
12.  15804  PhD Irena Kozjek Škofic  Pharmacy  Researcher  2010 - 2013  74 
13.  21626  Urška Levec Jazbinšek    Technical associate  2009 - 2013 
14.  12276  PhD Barbara Modec  Chemistry  Researcher  2009 - 2013  305 
15.  35576  PhD Jerca Pahor  Chemistry  Junior researcher  2012 - 2013  11 
16.  25633  PhD Ajda Podgoršek Berke  Chemistry  Junior researcher  2009  60 
17.  33334  PhD Rok Prebil  Chemistry  Junior researcher  2010 - 2013  24 
18.  35481  PhD Katarina Starkl Renar  Chemistry  Junior researcher  2012 - 2013  19 
19.  26547  PhD Gaj Stavber  Chemistry  Junior researcher  2009  58 
20.  06058  PhD Stojan Stavber  Chemistry  Researcher  2009 - 2013  310 
21.  27823  PhD Jerneja Šauta Ogorevc  Chemistry  Junior researcher  2009 - 2013  14 
22.  06061  PhD Boris Šket  Chemistry  Researcher  2011 - 2013  349 
23.  16025  PhD Elizabeta Tratar Pirc  Chemistry  Researcher  2009 - 2013  126 
24.  30890  PhD Dejan Vražič  Chemistry  Junior researcher  2009 - 2013  16 
25.  01317  PhD Marko Andrej Zupan  Chemistry  Researcher  2009 - 2011  459 
26.  16026  PhD Marija Zupančič  Chemistry  Researcher  2009 - 2013  139 
Organisations (2)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0103  University of Ljubljana, Faculty of Chemistry and Chemical Technology  Ljubljana  1626990  23,283 
2.  0106  Jožef Stefan Institute  Ljubljana  5051606000  91,322 
Abstract
New platinum coordination compounds will be prepared reacting cis-diamindichloroplatinum(II) and haloplatinates with organic ligands. Interactions of metal ions with biological macromolecules will be studied by quantummechanical modeling and the results compared with EXAFS measurements. Thin films appropriate for sensors will be developed. The mechanisms of halogen introduction into organic molecules and their influence on biological activity of new molecules will be studied.
Significance for science
Materials that exhibit intensive fluorescence in solid state can be potentially used as organic electroluminescence devices, fluorescent sensors, and in photodynamic therapy. Transformation under the solvent-free reaction conditions contribute importantly to the reduction of use of solvents and enhance the cost efficiency. Reactions with high degree of the atomic economy were demonstrated in several cases, thus opening the potential feasibility of processes on a larger scale. Extensive results gave us sufficient knowledge to perform second research step – demonstration project of in situ stabilization of PTE.
Significance for the country
The results of the basic research achieved in the framework of the programme have considerable applicative impact since the application of the principles of green chemistry in new technologies is an essential priority in chemical and pharmaceutical industry. The most relevant importance of our inventions is those dealing with aerobic oxidative transformations of organic compounds accompanied with use of aqueous hydrogen peroxide as the oxidant in chemical synthesis. The knowledge get in the programme have already been used in the following cooperation with Slovene companies: - Krka Pharmaceuticals: Comercialisation of new protocols for APIes production developed in our laboratories should bring incomes measured in MIO euros - ACIES BIO; hightec Biotecnology Company. New protocols for synthesis of small molecules syntnones for biosynthesis of APIes developed in our laboratories are actually in preliminarily tested on laboratory and semi-pilot scale. When commercialized should result in MIO euros incomes. - Ecot; non human cosmetics productions; The regarding environmentally friendly new products (auto cosmetics, cleaning products..) developed in our laboratories have been already commercialized with cca 100.000 euros income. - Semenarna agrochemicals: The new gametocide developed and on laboratory scale prepared in our laboratories has demonstrated even better activity than those actually used in agrochemical treatment of wheat. If commercialized, its production should bring considerable income
Most important scientific results Annual report 2009, 2010, 2011, 2012, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2010, 2011, 2012, final report, complete report on dLib.si
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