Projects / Programmes source: ARIS

Klinični pomen posredovanih interakcij med membranskimi strukturami (Slovene)

Research activity

Code Science Field Subfield
3.03.00  Medical sciences  Neurobiology   

Code Science Field
3.01  Medical and Health Sciences  Basic medicine 
Evaluation (rules)
source: COBISS
Researchers (14)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  16104  PhD Apolonija Bedina Zavec  Biotechnology  Researcher  2009 - 2012  143 
2.  22482  MSc Goran Bobojević  Computer science and informatics  Researcher  2009 - 2010  12 
3.  15647  PhD Klemen Bohinc  Physics  Researcher  2010  485 
4.  28540  PhD Matej Daniel  Systems and cybernetics  Researcher  2009  96 
5.  21314  PhD Miha Fošnarič  Physics  Researcher  2010 - 2012  164 
6.  04634  PhD Aleš Iglič  Systems and cybernetics  Researcher  2009 - 2012  940 
7.  33030  PhD Doron Kabaso  Physics  Researcher  2010 - 2012  26 
8.  17935  Jožica Košir    Technical associate  2009 
9.  05916  PhD Veronika Kralj Iglič  Neurobiology  Head  2009 - 2012  844 
10.  27526  PhD Maruša Lokar  Biochemistry and molecular biology  Junior researcher  2009 - 2011  37 
11.  30689  PhD Šarka Perutkova  Medical sciences  Junior researcher  2009 - 2012  54 
12.  31673  PhD Roman Štukelj  Sport  Researcher  2009 - 2012  112 
13.  34203  PhD Ekaterina Yurieva Gongadze  Neurobiology  Researcher  2011 - 2012  71 
14.  27568  PhD Jasna Zelko  Physics  Researcher  2009 - 2012  27 
Organisations (3)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0381  University of Ljubljana, Faculty of Medicine  Ljubljana  1627066  45,049 
2.  0382  University of Ljubljana, Faculty of Health Sciences  LJUBLJANA  1627155  14,518 
3.  1538  University of Ljubljana, Faculty of Electrical Engineering  Ljubljana  1626965  27,374 
Significance for science
Results of the project have proved in favor of hypothesis that mediated interaction between membranous structures is an important mechanism in inter cell communication and thereby clinically relevant. Attention was devoted to three segments of biophysics: theoretical, experimental and clinical. In the field of theoretical biophysics the results of the project contribute to elucidation of mediated interactions in living systems that could be relevant in suppression of microvesiculation. Results also contribute to the field of theoretical physics by further development of a density functional theory of solutions and stating and solving of the variational problem considering minimization of the curvature-dependent free energy of the system subject to local and global constraints. In the field of experimental biophysics the results of the project contribute to elucidation of mechanisms of intercellular communication which represent the basis of the functioning of organisms. In the field of clinical biophysics the results of the project contribute to implementation of the understanding of the above described basic processes into diagnostic and therapeutic procedures in cancer. We published 40 scientific papers, 31 conference proceedings, 7 chapters in monographies, collaborated in 20 lectures and applied for 1 patent. In conncetion with the project, 7 doctoral theses were defended and 3 student works were awarded.
Significance for the country
Results of the project are important for Slovenija because the project considered basic mechanisms that underlay widespread diseases such as cancer, thromboembolic events and inflammation. Improved knowledge will contribute to better determination, prevention and treatment of these diseases. Colleagues who work directly with patients will use the improved knowledge which will have positive medical, social and economic impact. Elaborated methods and procedures will lead to production of the new diagnostic equipment which will increase income and employment in the industry. Within the project knowledge was transmitted to young scientsts. 7 PhD theses were defended from the contents of the project. Collaboration with scientists abroad increased the impact of Slovenia. The project is important for the identity of Slovenes because it promoted scientific work that originates in Slovenia and is leaded from Slovenia.
Most important scientific results Annual report 2009, 2010, 2011, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2009, 2010, 2011, final report, complete report on dLib.si
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