Filters
cris logo
-
New search Filters
Select from list
Displayed from Show more
You have reached the maximum number of displayed search results.
All results displayed
No results are available for the search performed
Displayed from
You have reached the maximum number of displayed search results.
All results displayed
Loading results
Obtaining statistical data

Projects / Programmes source: ARIS

Varnost in klinična učinkovitost izločkov ličink muhe Lucilia sericata pri zdravljenju okužb ran (Slovene)

Edit
Research activity

Code Science Field Subfield
3.01.00  Medical sciences  Microbiology and immunology   

Code Science Field
3.01  Medical and Health Sciences  Basic medicine 
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (10)
no. Code Name and surname Research area Role Period No. of publications
1.  08312  PhD Bojana Beovič  Microbiology and immunology  Head  2009 - 2012  461 
2.  10802  PhD Matej Cimerman  Neurobiology  Researcher  2009 - 2012  263 
3.  05935  PhD Nina Gunde-Cimerman  Biotechnology  Researcher  2009 - 2012  1,259 
4.  28662  PhD Domen Jaklič  Microbiology and immunology  Researcher  2009 - 2010  34 
5.  11330  PhD Tatjana Lejko-Zupanc  Microbiology and immunology  Researcher  2009 - 2012  369 
6.  28753  Milica Lukić  Neurobiology  Researcher  2009 - 2012  75 
7.  16239  PhD Dragica Smrke  Neurobiology  Researcher  2009 - 2012  483 
8.  23963  PhD Silva Sonjak  Biotechnology  Researcher  2009 - 2011  58 
9.  18510  PhD Martina Turk  Biochemistry and molecular biology  Researcher  2012  192 
10.  31476  Suzana Vrenko    Technical associate  2009 - 2012  0 
Organisations (2)
no. Code Research organisation City Registration number No. of publications
1.  0312  University Medical Centre Ljubljana  Ljubljana  5057272000  77,458 
2.  0481  University of Ljubljana, Biotechnical Faculty  Ljubljana  1626914  66,322 
Significance for science
Treatment of wounds with maggots was well known in remote history. More recently it was used during the war conflicts in 20th century. Again, the maggot treatment is re-gaining its popularity because of increasing antimicrobial resistance. On individual level, antimicrobial resistance is most challenging in patients with chronic problems and repetitive antibiotic treatment such as patients with chronic wounds. Studies have shown that the efficacy of the maggots depends upon the bioactive ingredients of excretions/secretions (E/S). The E/S has proteolytic, antibacterial, and antifunfal activity. Besides, the E/S stimulates the wound healing. The study on clinical efficacy and safety of E/S in the treatment of chronic wounds is the first clinical trial which shows that the maggot treatment may be replaced by the treatment with the topical application of the E/S. The study confirms the in vitro results pointing out that not maggots themselves but the E/S are responsible for the activity in the wound treatment. The study confirms some other in vitro tests of the E/S: proteolysis seems to be the most prominent effect, the antibacterial effect was most prominent against Gram-positive bacteria. The healing effect was least visible although not absent. Clinical proof of the efficacy of E/S in chronic inflammed wounds without live maggots represents stimulation for further investigation of E/S ingredients and their mechanisms of action.
Significance for the country
The E/S alginate gel for topical wound treatment was prepared under experimental conditions in university laboratories. Optimisation of the procedures, which would standardize the procedures and make them less expensive, might lead to the development of commercially available medical device for wound treatment.
Most important scientific results Annual report 2009, 2011, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2009, 2011, final report, complete report on dLib.si
Confirmation required
Views history
Favourite