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Projects / Programmes source: ARIS

Sinteza in funkcionalizacija kompozitnih nanokroglic za zgodnje odkrivanje neurodegenerativnih bolezni (Slovene)

Research activity

Code Science Field Subfield
2.09.05  Engineering sciences and technologies  Electronic components and technologies  Vacuum technologies 

Code Science Field
2.11  Engineering and Technology  Other engineering and technologies 
Evaluation (rules)
source: COBISS
Researchers (17)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  01694  Zlatko Bele  Electronic components and technologies  Researcher  2009 - 2012  17 
2.  28540  PhD Matej Daniel  Systems and cybernetics  Researcher  2009  96 
3.  29520  PhD Kristina Eleršič Filipič  Biochemistry and molecular biology  Junior researcher  2009 - 2012  96 
4.  18635  Tatjana Filipič    Technical associate  2009 - 2012  24 
5.  21443  PhD David Haložan  Physics  Researcher  2009 - 2011  104 
6.  04634  PhD Aleš Iglič  Systems and cybernetics  Researcher  2009 - 2012  969 
7.  33030  PhD Doron Kabaso  Physics  Researcher  2010 - 2012  26 
8.  21408  PhD Aleš Lapanje  Microbiology and immunology  Researcher  2012  354 
9.  29138  PhD Tomaš Mareš  Physics  Researcher  2009 
10.  10429  PhD Miran Mozetič  Electronic components and technologies  Researcher  2009 - 2012  1,352 
11.  17420  Fani Oven    Technical associate  2012  11 
12.  28383  PhD Janez Ivan Pavlič  Systems and cybernetics  Junior researcher  2009  35 
13.  01718  PhD Iztok Šorli  Electronic components and technologies  Researcher  2009 - 2012  63 
14.  20048  PhD Alenka Vesel  Electronic components and technologies  Head  2009 - 2012  689 
15.  29275  PhD Tjaša Vrlinič  Engineering sciences and technologies  Researcher  2009 - 2011  16 
16.  34203  PhD Ekaterina Yurieva Gongadze  Neurobiology  Researcher  2012  72 
17.  16040  PhD Alexis Zrimec  Biology  Researcher  2009 - 2011  225 
Organisations (3)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  90,600 
2.  0341  MIKROIKS, microelectronics engineering, consulting and service  Ljubljana  5286646  70 
3.  1538  University of Ljubljana, Faculty of Electrical Engineering  Ljubljana  1626965  27,738 
Significance for science
A major drawback of population ageing in developed countries is an enormous increase of neurodegenerative diseases. According to the late statistics, a third of population older than 60 years exhibit symptoms of such diseases. Recent results obtained in European centres for investigation of the diseases showed that they are due to extraordinary increase of the prion-like molecules in the body fluids, especially cerebrospinal fluid and blood. Therefore, it is very important to detect specific disease in its early stage. Since the concentration of prions is very small, there was a need to develop a method for their separation from biological samples. We have developed two new procedures for synthesis of magnetic composite particles. The first procedure includes the synthesis of magnetic liposomes, and the other one includes the synthesis of magnetic sponge particles. Both composite particles have some certain advantages. Liposomes, which are bilayered phospholipid vesicles, are biodegradable particles, while the sponge particles, which are made of calcium carbonate matrix, are more stable particles compared with the liposomes. Both types of magnetic composite particles have many potential uses in medicine. They can not be used just as a method for the separation of specific substances from biological fluids, but also as carriers of therapeutic drugs to the specific targets. With appropriate external magnetic field is be possible to move the magnetic particles to the desired position. By this means we offer a new approach to local treatment of certain diseases.
Significance for the country
To the best of our knowledge there are not many groups in Slovenia performing research that leads to development of new products for biomedical applications. Such products are characterized by high value added. The results obtained within this project will enhance research activities in this field which is a priority scientific topic in the developed countries worldwide. Our activities within the project enable Slovenian partners to compete with groups in the developed countries and open a niche which is characterized by extremely high value added.
Most important scientific results Annual report 2009, 2010, 2011, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2009, 2010, 2011, final report, complete report on dLib.si
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