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Projects / Programmes source: ARRS

Sinteza in funkcionalizacija kompozitnih nanokroglic za zgodnje odkrivanje neurodegenerativnih bolezni (Slovene)

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Research activity

Code Science Field Subfield
2.09.05  Engineering sciences and technologies  Electronic components and technologies  Vacuum technologies 

Code Science Field
2.11  Engineering and Technology  Other engineering and technologies 
Evaluation (rules)
source: COBISS
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (17)
no. Code Name and surname Research area Role Period No. of publications
1.  01694  Zlatko Bele  Engineering sciences and technologies  Researcher  2009 - 2012  17 
2.  28540  PhD Matej Daniel  Engineering sciences and technologies  Researcher  2009  95 
3.  29520  PhD Kristina Eleršič Filipič  Natural sciences and mathematics  Junior researcher  2009 - 2012  94 
4.  18635  Tatjana Filipič    Technician  2009 - 2012  24 
5.  21443  PhD David Haložan  Natural sciences and mathematics  Researcher  2009 - 2011  99 
6.  04634  PhD Aleš Iglič  Engineering sciences and technologies  Researcher  2009 - 2012  924 
7.  33030  PhD Doron Kabaso  Natural sciences and mathematics  Researcher  2010 - 2012  26 
8.  21408  PhD Aleš Lapanje  Medical sciences  Researcher  2012  316 
9.  29138  PhD Tomaš Mareš  Natural sciences and mathematics  Researcher  2009  0 
10.  10429  PhD Miran Mozetič  Engineering sciences and technologies  Researcher  2009 - 2012  1,323 
11.  17420  Fani Oven    Technician  2012  11 
12.  28383  PhD Janez Ivan Pavlič  Engineering sciences and technologies  Junior researcher  2009  35 
13.  01718  PhD Iztok Šorli  Engineering sciences and technologies  Researcher  2009 - 2012  63 
14.  20048  PhD Alenka Vesel  Engineering sciences and technologies  Principal Researcher  2009 - 2012  662 
15.  29275  PhD Tjaša Vrlinič  Engineering sciences and technologies  Researcher  2009 - 2011  16 
16.  34203  PhD Ekaterina Yurieva Gongadze  Medical sciences  Researcher  2012  70 
17.  16040  PhD Alexis Zrimec  Natural sciences and mathematics  Researcher  2009 - 2011  225 
Organisations (3)
no. Code Research organisation City Registration number No. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  85,680 
2.  0341  MIKROIKS, microelectronics engineering, consulting and service  Ljubljana  5286646  70 
3.  1538  University of Ljubljana, Faculty of Electrical Engineering  Ljubljana  1626965  26,953 
Significance for science
A major drawback of population ageing in developed countries is an enormous increase of neurodegenerative diseases. According to the late statistics, a third of population older than 60 years exhibit symptoms of such diseases. Recent results obtained in European centres for investigation of the diseases showed that they are due to extraordinary increase of the prion-like molecules in the body fluids, especially cerebrospinal fluid and blood. Therefore, it is very important to detect specific disease in its early stage. Since the concentration of prions is very small, there was a need to develop a method for their separation from biological samples. We have developed two new procedures for synthesis of magnetic composite particles. The first procedure includes the synthesis of magnetic liposomes, and the other one includes the synthesis of magnetic sponge particles. Both composite particles have some certain advantages. Liposomes, which are bilayered phospholipid vesicles, are biodegradable particles, while the sponge particles, which are made of calcium carbonate matrix, are more stable particles compared with the liposomes. Both types of magnetic composite particles have many potential uses in medicine. They can not be used just as a method for the separation of specific substances from biological fluids, but also as carriers of therapeutic drugs to the specific targets. With appropriate external magnetic field is be possible to move the magnetic particles to the desired position. By this means we offer a new approach to local treatment of certain diseases.
Significance for the country
To the best of our knowledge there are not many groups in Slovenia performing research that leads to development of new products for biomedical applications. Such products are characterized by high value added. The results obtained within this project will enhance research activities in this field which is a priority scientific topic in the developed countries worldwide. Our activities within the project enable Slovenian partners to compete with groups in the developed countries and open a niche which is characterized by extremely high value added.
Most important scientific results Annual report 2009, 2010, 2011, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2009, 2010, 2011, final report, complete report on dLib.si
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