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Projects / Programmes source: ARIS

Metoda enovitega generiranja mili, mikro in nanosekundnih elektropermeabilizacijskih signalov za učinkovito gensko elektrotransfekcijo (Slovene)

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Research activity

Code Science Field Subfield
2.06.07  Engineering sciences and technologies  Systems and cybernetics  Biomedical technics 
Evaluation (rules)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Researchers (1)
no. Code Name and surname Research area Role Period No. of publications
1.  25421  PhD Matej Reberšek  Systems and cybernetics  Head  2009 - 2011  165 
Organisations (1)
no. Code Research organisation City Registration number No. of publications
1.  1538  University of Ljubljana, Faculty of Electrical Engineering  Ljubljana  1626965  27,756 
Significance for science
By developing new prototype electropermeabilization devices we enable the use of a wider spectrum of electrical parameters for research on cell membrane electropermeabilization and thus pioneer work in the field of electropermeabilization, a clearer insight into the method, and optimization of existing applications in biotechnology and medicine. Research with the combination of electrical pulses was already expanded from gene electrotransfer to inactivation of bacteria in water, equivalent pulse parameters for electroporation, electrofusion, and electroporation of endocytotic vesicles and mitohondria.
Significance for the country
The results acquired within the project were presented at scientific conferences and submitted as articles to SCI-ranked journals which contributes to the further increase in scientific prominence of the research group, as well as of the Republic of Slovenia as a whole. The knowledge acquired during the course of the project was transfered to the education process through an international postgraduate course Electroporation based technologies and treatments, and through the education program within the Faculty of Electrical Engineering. With the development of highvoltage nanosecond generators we have become one of the few groups in Europe that can produce such devices for applications in biotechnology.
Most important scientific results Annual report 2009, 2010, final report, complete report on dLib.si
Most important socioeconomically and culturally relevant results Annual report 2009, 2010, final report, complete report on dLib.si
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