Aminokisline kot gradniki v organski sintezi (Slovene)

Code

J1-7343 (C) - included in ARRS records

Head

PhD Marijan Kočevar

Period

1/1/1996 - 6/30/2001

Science

Natural sciences and mathematics (7)
Engineering sciences and technologies (1)
Medical sciences (1)
Other (1)

Reseacher status

Researcher (9)
Junior expert or technical associate (1)
Junior researcher (0)
Researcher/expert (0)
Private researcher (0)

Education

Doctor's degree (9)
Other (1)

Sex

Woman (1)
Man (9)

Status

Active (7)
Retired (3)

No. of publications

1–9 (1)
10–99 (2)
100–999 (7)

Projects / Programmes source: ARRS

source: ARRS

Aminokisline kot gradniki v organski sintezi (Slovene)

Research activity

Code	Science	Field	Subfield
1.04.04	Natural sciences and mathematics	Chemistry	Organic chemistry

Code	Science	Field
P003	Natural sciences and mathematics	Chemistry
P390	Natural sciences and mathematics	Organic chemistry

Keywords

Amino acids, unsaturated; catalysis, homogeneous or heterogeneous; asymmetric synthesis; hydrogenation; oxygenation; high-pressure research; heterocycles; pyrons; benzopyrans; benzofurans; 5(4H)-oxazolones; dioxiranes.

Evaluation (rules)

source: COBISS

Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases

source: WoS

source: Scopus

source: COBISS

Researchers (10)

no.	Code	Name and surname	Research area	Role	Period	No. of publicationsNo. of publications
1.	08385	PhD Janez Cerkovnik	Natural sciences and mathematics	Researcher	2000 - 2001	166
2.	21173	PhD Marjan Ješelnik	Engineering sciences and technologies	Researcher	1996 - 2001	29
3.	17138	Zdenka Kadunc		Researcher	2000 - 2001	2
4.	11398	PhD Vladimir Kepe	Medical sciences	Researcher	1996 - 2001	43
5.	03904	PhD Marijan Kočevar	Natural sciences and mathematics	Principal Researcher	1999 - 2001	572
6.	20063	PhD Krištof Kranjc	Natural sciences and mathematics	Researcher	1996 - 2001	243
7.	03374	PhD Ivan Leban	Natural sciences and mathematics	Researcher	1996 - 2001	539
8.	05044	PhD Andrej Petrič	Natural sciences and mathematics	Researcher	1998 - 2001	205
9.	02310	PhD Slovenko Polanc	Natural sciences and mathematics	Researcher	1996 - 2001	549
10.	19405	PhD Franc Požgan	Natural sciences and mathematics	Researcher	1996 - 2001	360

Organisations (1)

no.	Code	Research organisation	City	Registration number	No. of publicationsNo. of publications
1.	0103	University of Ljubljana, Faculty of Chemistry and Chemical Technology	Ljubljana	1626990	22,058

Abstract

We investigate novel synthetic approaches to potentially biologically active com--pounds containing amino acid units in their structure. The emphasis is given on unsatu-rated dehydroamino acid derivatives, elucidation of their structure and further selective or stereo-selective conversions: reductions, oxidations, transformations into various heterocyclic systems, etc. We are also investigating structure – activity relationship and using mod-ern methods for the design of biologically active compounds, including molecular model-ling by the application of experimentally obtained data on the basis of NMR spectra. In particular, we are interested in selective transformations into (Z)- and (E)-derivatives of di-de-hydro-amino acids, possibility of their interconversion and their further transformations. Recently, such compounds were extensively used as excellent synthons for enantioselective homogenous catalytic hydrogenation as well as to find the best catalysts for such conver-sions. We are also planing to study stereoselective reduction of prochiral ketones by the appli-ca-tion of various reducing agents, such as for example optically active complexes of transition metals, homogeneous or heterogeneous catalytic hydrogenation. On the other hand, we plan to investigate se-lec-tive or stereoselective oxidations of unsaturated organic compounds with ecologically pure oxidants, such as peroxides, for example hydrogen peroxide or cyclic dimethyldioxirane. This field of investigation belongs to the preferential investigation in COST D12 program within EU (Organic Transformations: Selective Processes and Asymmetric Catalysis). We are also planing to start the research at the high pressures (č15 kbar), at which some reactions (cycloadditions, substitutions, etc.) take place easier than at the normal condi-tions. Here, it is often easily to study mechanisms, due to the easier capture of intermediates than at the normal pressure.