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Projects / Programmes source: ARIS

Serumske vrednosti cisteinskih proteinaz katepsinov B, H in L in njihovih inhibitorjev stefinov in cistatinov kot pokazateljev diagnoze (Slovene)

Research activity

Code Science Field Subfield
1.05.00  Natural sciences and mathematics  Biochemistry and molecular biology   

Code Science Field
P310  Natural sciences and mathematics  Proteins, enzymology 
B200  Biomedical sciences  Cytology, oncology, cancerology 
Keywords
cathepsins, stefins, cystatin C, cancer, diagnosis, prognosis
Evaluation (rules)
source: COBISS
Researchers (9)
no. Code Name and surname Research area Role Period No. of publicationsNo. of publications
1.  10291  PhD Nina Cimerman  Pharmacy  Researcher  1999 - 2001  117 
2.  04648  PhD Janko Kos  Biotechnical sciences  Head  1998 - 2001  1,166 
3.  06394  Marta Krašovec  Pharmacy  Researcher  1998 - 2001  83 
4.  03171  PhD Aleksandra Markovič-Predan  Medical sciences  Researcher  1998 - 2001  284 
5.  14315  PhD Ana Schweiger  Biochemistry and molecular biology  Researcher  1998 - 2001  62 
6.  17096  Andreja Sekirnik  Biochemistry and molecular biology  Researcher  1998 - 2001  31 
7.  11949  PhD Borut Štabuc  Oncology  Researcher  2000 - 2001  679 
8.  07195  PhD Ivan Vrhovec  Oncology  Researcher  1998 - 2001  116 
9.  18286  PhD Tina Zavašnik Bergant  Biochemistry and molecular biology  Researcher  1998 - 2001  138 
Organisations (3)
no. Code Research organisation City Registration number No. of publicationsNo. of publications
1.  0106  Jožef Stefan Institute  Ljubljana  5051606000  91,992 
2.  0259  Krka, tovarna zdravil, d.d., Novo mesto (Slovene)  Novo mesto  5043611  3,819 
3.  0302  Institute of Oncology Ljubljana  Ljubljana  5055733000  15,793 
Abstract
The objective of this project is to determine levels of cysteine proteinases cathepsins B, H and L and their inhibitors stefins A and B and cystatin C in sera of patients with malignant melanoma and colorectal cancer using quantitative immunoenzyme assays and to define their potential for prediction of diagnosis, prognosis and response to different chemotherapy in these cancer patients.
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