Projects / Programmes source: ARIS

Tissue receptors for phospholipases A2 from snake venoms

Edit
Research activity

Code Science Field Subfield
1.05.00  Natural sciences and mathematics  Biochemistry and molecular biology   

Code Science Field
P310  Natural sciences and mathematics  Proteins, enzymology 
P340  Natural sciences and mathematics  Lipids, steroids, membranes 
Keywords
phospholipase A2, neurotoxin, synapse, receptor, neurotransmitter
Evaluation (metodology)
source: COBISS
Evaluation of bibliographic research performance indicators according to ARIS methodology
Citations Citations for bibliographic records in COBIB.SI that are linked to records in citation databases
source: WoS source: Scopus source: COBISS
Organisations (1) , Researchers (6)
0106  Jožef Stefan Institute
no. Code Name and surname Research area Role Period No. of publications
1.  01088  PhD Vladimir Cotič  Biochemistry and molecular biology  Researcher  1999 - 2001  48 
2.  01083  PhD Franc Gubenšek  Biochemistry and molecular biology  Researcher  1998 - 2001  576 
3.  00412  PhD Igor Križaj  Biochemistry and molecular biology  Head  1998 - 2001  769 
4.  18802  PhD Adrijana Leonardi  Biochemistry and molecular biology  Researcher  1999 - 2001  178 
5.  11058  PhD Alenka Pariš  Biochemistry and molecular biology  Researcher  1998 - 2001  23 
6.  04570  PhD Jože Pungerčar  Biochemistry and molecular biology  Researcher  1998 - 2001  346 
Abstract
Certain phospholipases A2 have evolved different pharmacological activities during evolution. In the proposed project we plan to investigate tissue receptors for presynaptically neurotoxic phospholipases A2. The main goal of the project is to isolate the neuronal receptor of ammodytoxins, neurotoxic phospholipases A2 from the long-nosed viper venom. This research will contribute to understanding the mechanism of action of ammodytoxins and to their potential use as specific ligands in neurobiology and medicine.
Confirmation required
Views history
Favourite