In January 2020 the NIJZ initiated the establishment of a national expert working group, which will prepare National Recommendations for a sufficient supply of vitamin D in the population on the basis of evidence (also obtained within the framework of this project). Other project partners are also members of the working group.
F.30 Professional assessment of the situation
Goal: To investigate efficiency of two months of treatment using 1000 IU of vitamin D3 per day using three different VitD formulations on human subjects with suboptimal Vitamin D status. Method: A randomized controlled intervention study was conducted on 105 subjects (aged 18–65 years) with suboptimal vitamin D status (12–20 mcg/L). Subjects were randomized into four groups—a control group which did not receive supplemental Vitamin D, and three treatment groups, receiving (A) oil-based Valens vitamin D oral spray; (B) water-based Valens vitamin D oral spray; or (C) Vitamin D capsules with starch-adsorbed vitamin D. The trial was conducted in Slovenia during winter time; supplementation started in January and ended in March. Results: Supplementation with Vitamin D (1000 IU daily) during winter resulted in considerable increase in average serum VitD levels for 13 mg/L (from 15 ± 2 mcg/L to 28 ± 7 mcg/L), while no statistically important differences were observed between the tested formulations. On the other hand, control serum VitD level in the control group was further lowered from January to March. Conclusions: All three tested VitD formulations were efficient in improving suboptimal VitD status; however, the dosage of 1000 IU daily might not be sufficient for optimal VitD status during winter months. After 2 months of supplementation, serum VitD levels were still below 30 mcg/L in 77% of the subjects.
F.07 Improvements to an existing productCOBISS.SI-ID: 40289285