The nmr2st program package for assignment of NOESY spectra of peptides and proteins follows the NMR spectroscopic and modelling work; written in ANSI C it can be run on many platforms (Windows, UNIX, linux) and is used in research units in Germany and italy (see http://www.primus.co.nr/nmr2st). The development of some parts of the software has been continued after the release of some key algorithms in the paper in J. comput. chem. in 2006.
F.15 Development of a new information system/databases
COBISS.SI-ID: 3547674Young researcher Mateja Zorko - involved in the project - won the Krka award in 2008 Young researcher Nuša Resman - involved in the project
D.09 Tutoring for postgraduate students
COBISS.SI-ID: 4042522We have prepared a new type of peptide inhibitors of substance INT INT domain adapter protein. We prepared two types of peptides that can penetrate into the cells, and showed their performance. Peptide can prevent the activation of several TLRjev through binding to the cytosolic adapter proteins. The potential use of these peptides for the inhibition of inflammation, which is important in many diseases.
F.32 International patent
COBISS.SI-ID: 4380954The invited lecture presebted results of research in cell signalling inhibition using peptides. Besides inhibitors of LPS signalling we prepared inhibitors that act by binding to proteins involved in cell signalling.
B.04 Guest lecture
COBISS.SI-ID: 4181018