Mycobacterium avium subsp. hominissuis is an opportunistic pathogen often isolated from pigs and humans. Genetic diversity of 114 pig and human isolates was investigated using IS1245 RFLP. Identical profiles were found in isolates from pigs, humans and from both hosts. The proportion of clustered isolates varied depending on the cluster limits. Using IS1245 RFLP, it was possible to detect monoclonal, polyclonal and recent infections and to monitor the genetic variability of the strains from individual patients. Our findings indicate the environment as the source of infection for both hosts.
COBISS.SI-ID: 2990458
Patients who underwent R0 resection for colorectal cancer during the period 1995-2000 showed a significantly improved 5-year survival rate compared to those operated between 1991 and 1995. Improved survival in these patients is to a great extent attributable to improvements in clinical practice combining surgery and adjuvant therapy.
COBISS.SI-ID: 24461785