L-Carnitine is used extensively in functional foods and food supplements and its enantiomeric purity is very important. A new derivatization procedure and chiral gas chromatographic method with flame ionization detector, using a cyclodextrin based stationary phase, enables prompt, simple, and inexpensive determination of the enantiomeric ratio of L- and D-carnitine via ß-acetoxy-?-butyrolactone. Transformation of carnitine to the butyrolactone was optimized for maximum conversion (~98%) and minimum racemization (none observed) and time consumption.
B.03 Paper at an international scientific conference
COBISS.SI-ID: 4251930We developed a new TLC analytical method for the deterination of [alpha]-lipoic acid content in drug formulations and food supplements. Validated method is useful for the determination of this compound, which was demonstrated with analyses of products available on Slovenian and Serbian market.
F.35 Other
COBISS.SI-ID: 4238874Two awards at the 15th International Symposium on Separation Sciences'' (2.-4.9.2009, Siófok, Hungary): 1. Vesna Glavnik: Award for the best poster ("Comparison of TLC and HPLC Methods for Determination of (-)-Epicatechin and Procyanidin B2 in Chocolate"). The award is a one-year subscription to the "Journal of Planar Chromatography – Modern TLC". 2. Alen Albreht: Award for excellent poster presentation ("A novel derivatization procedure and chiral GC method for the enantiomeric determination of L- and D-carnitine"). The award is a one-year subscription to "Chromatographia".
E.02 International awards
COBISS.SI-ID: 4252186We organized a conference, which was held from 16th to 18th October 2009 at the National Institute of Chemistry (NIC). The participants from Slovenia and abroad were researchers, who deal with exploring the role of CoQ10 in nature. Among them was also the president of the International Coenzyme Q10 Association and the introductory speaker prof. dr Littarru from the Faculty of Medicine, Ancona (Italy),. An important part was the panel discussion for experts and consumers of CoQ10. Co-organizer: Perutnina Ptuj d. d., Valens d.o.o., University of Maribor and NIC.
B.06 Other
COBISS.SI-ID: 247894272The aims of this study were to evaluate the bioavailability, tolerance, and possible side effects of the fruit syrup with CoQ10 in treatment of children with mitochondrial diseases. This formulation significantly increased the plasma concentration of CoQ10 in treated children.
F.02 Acquisition of new scientific knowledge
COBISS.SI-ID: 4303386