Key components of our research, i.e. ability of abstract thinking and the building representations of the structure and dynamics of the microscopic and macroscopic systems have been used as the basis for the development of new teaching materials that were presented in different works, including the Planinšič G et al. Eur.J.Phys. 32 (2011) and in invited lecture and workshop at Rutgers University, NJ, USA. A lot of work has been done on the introduction of the program content in teaching science subjects in secondary school level and at the level of the first cycle of university education (Planinšič G , Conference on teaching physics, chemistry and mathematics, SASA, 2011; Planinšič G, Proteus 73 (2011); Planinšič G Vzgoja.Izobr. 42-43 (2011)).
D.10 Educational activities
COBISS.SI-ID: 2316132Within area A2 Structure and function of biological membranes we entered into one of the hottest topics in biophysics, study of the interactions between new materials and cells based on the last year MG2 goal achievement (FMS). FMS development enables us the research of in -cell localization of various nanomaterials used for antimicrobial protection of the surfaces. In addition, FMS was used to unravel the interaction between cells and gelatin gels as scaffolds for large cartilage defects repair. Bleaching problem was solved with a special algorithm developed to neutralize the bleaching effect in spectral analysis. FMS system was optimized and upgraded with system for micromanipulation to enable measurements of the force between the cells and the scaffolds. Several new fluorescent and double fluorescent-spin amphiphilic probes have been designed and synthesized to enable hybrid techniques. The results lead to patent preparation and interest of the two biotech slovenian companies: Animacel and Educell, which were involved in the applied project preparation together with CO NAMASTE.
F.21 Development of new health/diagnostic methods/procedures
COBISS.SI-ID: 24859687We confirmed our assumption that thrombolysis is not just a biochemical process in which there is complete degradation of fibrin, but under the influence of rapid blood flow it leads to formation of strong mechanical forces to the surface of a blood clot that result from blood viscosity. These forces cause breakage of large parts of the clot formed by the fibrin network and blood cells (primarily erythrocytes). With optical microscopy we showed that the size of these clusters largely depends on blood flow explaining why the thrombolysis is much faster in faster flow than in than slow flow. We also pointed to the connection between blood flow and place of blood clot as well as the structure of the clot. With this study we contribute significantly to the understanding of the clot formation.
F.22 Improvement to existing health/diagnostic methods/procedures
COBISS.SI-ID: 24978983